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Volume 25, Number 1—January 2019
Dispatch

Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China

Lu Sun1, Yan Chen1, Danying Wang, Haiping Wang, Dandan Wu, Keren Shi, Ping Yan, and Yunsong YuComments to Author 
Author affiliations: Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou, China (L. Sun, Y. Chen, D. Wang, H. Wang, D. Wu, K. Shi, Y. Yu); Fuyang Hospital of Traumatology and Orthopedics of Traditional Chinese Medicine, Hangzhou (P. Yan); Key Laboratory for Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou (Y. Yu)

Main Article

Figure 2

Virulence phenotype of MRSA ST398 isolates. A) Hemolysis analysis. The hemolytic activity of culture filtrates grown for 24 h was measured in triplicate at given dilutions. The mean and SE are shown. The statistical analysis used a 2-way analysis of variance between multiple groups. FY20 and FY22 were significantly stronger than other strains in dilution 1:4, 1:8, 1:16, and 1:32 (p<0.05). B) Abscess sizes in the mouse skin infection model. There were 4 mice per strain, and the mean and SE are

Figure 2. Virulence phenotype of MRSA ST398 isolates. A) Hemolysis analysis. The hemolytic activity of culture filtrates grown for 24 h was measured in triplicate at given dilutions. The mean and SE are shown. The statistical analysis used a 2-way analysis of variance between multiple groups. FY20 and FY22 were significantly stronger than other strains in dilution 1:4, 1:8, 1:16, and 1:32 (p<0.05). B) Abscess sizes in the mouse skin infection model. There were 4 mice per strain, and the mean and SE are shown. The statistical analysis used a 2-way analysis of variance to compare data for multiple groups. The abscess sizes of FY20 and FY22 were significantly larger than SR411 and the HL1 agr mutant (p<0.05) but were similar to SR389 and HL1 (p>0.05) at day 1, day 2, and day 3. MRSA, methicillin-resistant Staphylococcus aureus; OD, optical density; ST, sequence type.

Main Article

1These authors contributed equally to this article.

Page created: December 17, 2018
Page updated: December 17, 2018
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