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Volume 25, Number 1—January 2019
CME ACTIVITY - Synopsis

Enterovirus A71 Infection and Neurologic Disease, Madrid, Spain, 2016

Carmen Niño Taravilla1Comments to Author , Isabel Pérez-Sebastián1, Alberto García Salido, Claudia Varela Serrano, Verónica Cantarín Extremera, Anna Duat Rodríguez, Laura López Marín, Mercedes Alonso Sanz, Olga María Suárez Traba, and Ana Serrano González
Author affiliations: Hospital Infantil Universitario Niño Jesús, Madrid, Spain

Main Article

Table

Enterovirus serotype, localization of isolation, WHO clinical classification, and outcomes for 30 patients with enterovirus infection and neurologic disease, Madrid, 2016*

Patient no. Patient age/sex WHO clinical classification Enterovirus source Enterovirus serotype Patient outcome
1 2 mo/M Aseptic meningitis CSF Genotyped negative Recovered
2 16 d/F Aseptic meningitis CSF ND Recovered
3 3 mo/F Encephalitis Nasopharyngeal aspirate A71 Recovered
4 10 mo/F Encephalitis Nasopharyngeal aspirate A71 Recovered
5 12 mo/M Brainstem encephalitis Nasopharyngeal aspirate A71 Unknown
6 17 mo/F Brainstem encephalitis Nasopharyngeal aspirate Genotyped negative Unknown
7 21 mo/F Brainstem encephalitis Nasopharyngeal aspirate A71 Cerebellar dysfunction
8 22 mo/F Encephalitis Nasopharyngeal aspirate Rhinovirus Recovered
9 19 mo/M Encephalitis Nasopharyngeal aspirate A71 Unknown
10 18 mo/M Encephalitis Anal swab sample A71 Cerebellar dysfunction
11 2 y/M Brainstem encephalitis Nasopharyngeal aspirate A71 Recovered
12 2 y/M Cardiopulmonary failure Nasopharyngeal aspirate A71 Acquired brain damage
13 23 mo/F Cardiopulmonary failure Anal swab sample A71 Cerebellar dysfunction
14 2 y/M Encephalitis Nasopharyngeal aspirate B Recovered
15 3 y/M Brainstem encephalitis Nasopharyngeal aspirate A71 Recovered
16 3 y/F Brainstem encephalitis Anal swab sample A71 Recovered
17 3 y/F Cardiopulmonary failure Nasopharyngeal aspirate A71 Paresis of the right upper limb
18 4 y/F Brainstem encephalitis Nasopharyngeal aspirate A71 Cerebellar dysfunction
19 4 y/M Aseptic meningitis CSF ND Recovered
20 4 y/M Brainstem encephalitis Nasopharyngeal aspirate A71 Cerebellar dysfunction
21 4 y/M Aseptic meningitis CSF Echovirus Recovered
22 6 y/M Aseptic meningitis CSF ND Recovered
23 6 y/F Aseptic meningitis CSF Echovirus Recovered
24 7 y/M Brainstem encephalitis Nasopharyngeal aspirate A71 Cerebellar dysfunction
25 1 mo/M Encephalitis CSF A71 Recovered
26 4 y/M Encephalitis Nasopharyngeal aspirate A71 Recovered
27 5 y/M ANS dysfunction Nasopharyngeal aspirate A71 Cerebellar dysfunction
28 2 y/F Encephalitis Nasopharyngeal aspirate A71 Recovered
29 2 y/M Brainstem encephalitis Anal swab sample A71 Recovered
30 20 mo/M Brainstem encephalitis Anal swab sample A71 Peripheral facial paralysis

*ANS, autonomic nervous system; CSF, cerebrospinal fluid; ND, not done; WHO, World Health Organization.

Main Article

1These authors contributed equally to this article.

Page created: December 13, 2018
Page updated: December 13, 2018
Page reviewed: December 13, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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