Volume 25, Number 1—January 2019
Synopsis
Clinical and Radiologic Characteristics of Human Metapneumovirus Infections in Adults, South Korea
Hyun Jung Koo, Han Na Lee, Sang-Ho Choi, Heungsup Sung, Hwa Jung Kim, and Kyung-Hyun Do
Table 3
Clinical characteristics of patients associated with human metapneumovirus pneumonia, South Korea*
| Characteristic | URI, n = 270 | LRD, n = 579 | Univariate analysis |
Multivariable analysis |
|||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | ||||
| Age |
59.0 (49.3–69.8) |
66.0 (56.0–74.0) |
1.02 (1.01–1.03) |
<0.001 |
1.02 (1.01–1.03) |
0.001 |
|
| Male sex |
121 (45) |
321 (55) |
1.57 (1.17–2.09) |
0.002 |
0.95 (0.65–1.40) |
0.81 |
|
| Smoking | <0.001 | 0.01 | |||||
| Never | 209 (77) | 356 (61) | 1 | 1 | |||
| Former | 12 (4) | 39 (7) | 1.91 (0.98–3.73) | 0.59 | 1.66 (0.80–3.43) | 0.17 | |
| Current |
51 (19) |
182 (31) |
2.10 (1.47–2.99) |
<0.001 |
2.07 1.30–3.29) |
0.002 |
|
| Body mass index, kg/m2 |
23.4 (21.0–25.7) |
22.7 (20.1–25.4) |
0.97 (0.94–1.00) |
0.09 |
0.97 (0.93–1.00) |
0.07 |
|
| Diabetes mellitus | 79 (29) | 217 (37) | 1.47 (1.08–2.01) | 0.02 | 1.37 (0.96–1.95) | 0.08 | |
| Community-acquired pneumonia | 238 (88) | 516 (89) | 0.83 (0.53–1.30) | 0.41 | 1.10 (0.68–1.79) | 0.69 | |
| Other pathogen |
63 (23) |
140 (24) |
0.92 (0.66–1.30) |
0.64 |
1.05 (0.73–1.52) |
0.80 |
|
| Underlying condition | 0.002 | 0.003 | |||||
| Immunocompetent | 126 (47) | 333 (58) | 1 | 1 | |||
| Solid tumor | 68 (25) | 106 (18) | 0.59 (0.41–0.85) | 0.005 | 0.57 (0.38–0.84) | 0.005 | |
| SOT | 30 (11) | 29 (5) | 0.37 (0.21–0.63) | <0.001 | 0.35 (0.19–0.65) | 0.001 | |
| HCT | 1 (0.4) | 8 (1) | 3.03 (0.38–24.45) | 0.30 | 3.75 (0.44–31.85) | 0.23 | |
| HM | 20 (7) | 38 (7) | 0.72 (0.40–1.28) | 0.26 | 0.79 (0.43–1.45) | 0.45 | |
| Steroid use | 27 (10) | 63 (11) | 0.88 (0.54–1.45) | 0.62 | 0.72 (0.43–1.22) | 0.22 | |
*Values are no. (%) or median (interquartile range). HT, hematologic stem cell transplantation; HM, hematologic malignancy; LRD, lower respiratory tract disease; OR, odds ratio; SOT, solid organ transplants; URI, upper respiratory tract infection.
Page created: December 18, 2018
Page updated: December 18, 2018
Page reviewed: December 18, 2018
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