Volume 25, Number 1—January 2019
Synopsis
Clinical and Radiologic Characteristics of Human Metapneumovirus Infections in Adults, South Korea
Hyun Jung Koo, Han Na Lee, Sang-Ho Choi, Heungsup Sung, Hwa Jung Kim, and Kyung-Hyun Do
Table 4
Clinical characteristics associated with 30-day mortality rate for patients infected with HMPV, South Korea*
| Characteristic | Recovered, n = 802 | 30-day mortality rate, n = 47 | Univariate analysis |
Multivariable analysis |
|||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | ||||
| Age |
63.5 (53.0–73.0) |
67.0 (55.0–77.0) |
(0.99–1.04) |
0.15 |
1.02 (1.00–1.05) |
0.11 |
|
| Male sex |
416 (52) |
26 (55) |
0.87 (0.48–1.57) |
0.65 |
|||
| Smoking | 0.04 | 0.54 | |||||
| Never | 540 (67) | 25 (53) | 1 | 1 | |||
| Former | 48 (6) | 3 (6) | 1.35 (0.39–4.63) | 0.63 | 0.67 (0.15–3.04) | 0.61 | |
| Current |
214 (27) |
19 (40) |
1.92 (1.04–3.56) |
0.04 |
1.35 (0.69–2.64) |
0.39 |
|
| Body mass index, kg/m2 |
23.1 (20.5–25.6) |
20.5 (18.2–24.1) |
0.89 (0.79–0.95) |
0.001 |
0.86 (0.79–0.95) |
0.002 |
|
| Diabetes mellitus | 277 (35) | 19 (40) | 1.29 (0.71–2.35) | 0.41 | 1.48 (0.77–0.95) | 0.24 | |
| Community-acquired pneumonia | 715 (89) | 40 (85) | 0.70 (0.30–1.60) | 0.39 | 0.83 (0.32–2.11) | 0.69 | |
| Other pathogen |
193 (24) |
10 (21) |
0.86 (0.42–1.76) |
0.68 |
0.75 (0.35–1.60) |
0.45 |
|
| Underlying condition | 0.02 | 0.02 | |||||
| Immunocompetent | 443 (55) | 16 (34) | 1 | ||||
| Solid tumor | 157 (20) | 17 (36) | 3.00 (1.48–6.08) | 0.002 | 3.43 (1.58–7.44) | 0.002 | |
| SOT | 59 (7) | 0 | 0.00 (0.00–0.00) | 1.00 | 0.00 (0.00–0.00) | 1.00 | |
| HCT | 7 (0.9) | 2 (4) | 7.91 (1.52–41.1) | 0.01 | 9.19 (1.47–57.37) | 0.02 | |
| HM | 53 (7) | 5 (11) | 2.61 (0.92–7.42) | 0.07 | 3.44 (1.14–10.34) | 0.03 | |
| Steroid use | 83 (10) | 7 (15) | 2.34 (0.93–5.85) | 0.07 | 2.40 (0.91–6.34) | 0.08 | |
*Values are no. (%) or median (interquartile range). HCT, hematologic stem cell transplantation; HM, hematologic malignancy; OR, odds ratio; SOT, solid organ transplants.
Page created: December 18, 2018
Page updated: December 18, 2018
Page reviewed: December 18, 2018
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