Volume 25, Number 10—October 2019
CME ACTIVITY - Synopsis
Case Studies and Literature Review of Pneumococcal Septic Arthritis in Adults
Table 4
Patient age, y/sex | Antimicrobial drugs, initial intravenous therapy; duration, d | Antimicrobial drugs, change to oral therapy | Surgical intervention | Duration of antimicrobial therapy, d | Clinical outcome |
---|---|---|---|---|---|
90/M | Ceftriaxone and rifampin; 4 | Levofloxacin and rifampin | Arthrotomy and replacement of prosthetic joint | 42 | Recovered, regained baseline joint function |
93/F | Ceftriaxone and gentamicin; 5 | Levofloxacin and clindamycin | Arthrotomy and synovectomy | 120 | Recovered, regained baseline joint function |
34/M | Amoxicillin and gentamicin; 4 | Levofloxacin and amoxicillin | None | 42 | Recovered, moderately reduced range of motion |
68/M | Amoxicillin and gentamicin; 2 | NA | None | 2 | Died 2 d after admission from multiorgan failure related to colchicine overdose |
75/M | Amoxicillin and gentamicin, then amoxicillin and levofloxacin; 11 | Levofloxacin | None | 42 | Recovered, regained baseline joint function |
42/F | Vancomycin and gentamicin; 6 | Levofloxacin and rifampin | Arthrotomy | 42 | Recovered, moderately reduced range of motion |
80/F | Ofloxacin and cloxacillin; 1 | Amoxicillin | None | 42 | Recovered, regained baseline joint function |
61/F | Amoxicillin and levofloxacin and rifampin; 7 | Amoxicillin and rifampin | Arthrotomy | 42 | Recovered, regained baseline joint function |
57/F | Amoxicillin and gentamicin; 5 | Amoxicillin | None | 42 | Recovered, moderately reduced range of motion |
82/F | ND | ND | ND | ND | ND |
92/F | ND | ND | ND | ND | ND |
53/F | Ceftriaxone and gentamicin; 15 | Levofloxacin | None | 84 | Recovered, regained baseline joint function |
69/M | Amoxicillin and gentamicin; ND | ND | ND | ND | Recovered, regained baseline joint function |
82/F | Cefotaxime and gentamicin; 7 | Levofloxacin and rifampin | Arthrotomy | 47 | Recovered, moderately reduced range of motion |
57/M | Amoxicillin and gentamicin; 27 | Amoxicillin | Arthrotomy and synovectomy | 42 | Recovered, moderately reduced range of motion |
82/M | Amoxicillin and gentamicin; 10 | Amoxicillin | None | 42 | Recovered, regained baseline joint function |
*NA, not applicable; ND, no data.
1These authors contributed equally to this article.
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