Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 25, Number 10—October 2019
Research

Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus

Ruth Harvey, Giada MattiuzzoComments to Author , Mark Hassall, Andrea Sieberg, Marcel A. Müller, Christian Drosten, Peter Rigsby, Christopher J. Oxenford, and study participants
Author affiliations: National Institute for Biological Standards and Control—MHRA, Potters Bar, UK (R. Harvey, G. Mattiuzzo, M. Hassall, P. Rigsby); Charité-Universitätsmedizin Berlin, Berlin, Germany (A. Sieberg, M.A. Müller, C. Drosten); German Centre for Infection Research, Berlin (M.A. Müller, C. Drosten); World Health Organization, Lyon, France (C.J. Oxenford).

Main Article

Figure 3

Relative titers of the individual positive patient plasma sample against a reference standard in study of serologic assays for MERS-CoV. Each panel represents a MERS-CoV–positive patient plasma sample: sample 1 (A), sample 5 (B), sample 9 (C), sample 11 (D), sample 12 (E). In each panel, the first data column shows the spread of endpoint titers from all quantitative assays performed; the second and third columns show quantitative results expressed as a potency relative to either sample 4 (Tc Bov

Figure 3. Relative titers of the individual positive patient plasma sample against a reference standard in study of serologic assays for MERS-CoV. Each panel represents a MERS-CoV–positive patient plasma sample: sample 1 (A), sample 5 (B), sample 9 (C), sample 11 (D), sample 12 (E). In each panel, the first data column shows the spread of endpoint titers from all quantitative assays performed; the second and third columns show quantitative results expressed as a potency relative to either sample 4 (Tc Bovine IgG raised against whole virus) or sample 16 (high-positive serum pool A), In each case the sample used as a reference was assigned nominal potency of 1,000 and all other samples were expressed as relative to the reference sample. For each dataset, horizontal line indicates the mean; error bars show SEM. MERS-CoV, Middle East respiratory syndrome coronavirus.

Main Article

1Study participants who contributed data are listed at the end of this article.

Page created: September 17, 2019
Page updated: September 17, 2019
Page reviewed: September 17, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external