Table 5

Prevalence of Tuberculosis in Children After Natural Disasters, Bohol, Philippines

Kristy O. Murray, Nina T. Castillo-Carandang, Anna M. Mandalakas, Andrea T. Cruz, Lauren M. Leining, Salvacion R. Gatchalian

, on behalf of the PEER Health Bohol Pediatric Study Team

Author affiliations: Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA (K.O. Murray, A.M. Mandalakas, A.T. Cruz, L.M. Leining); University of the Philippines, Manila, Philippines (N.T. Castillo-Carandang, S.R. Gatchalian)

Main Article

Clinical and diagnostic findings for 16 persons with TB in cluster survey of TB in children in areas affected by 2013 natural disasters, Bohol, Philippines, 2016–2018*

Case no.	Natural disaster area	Age, y/sex	Known exposure to TB	History of signs/symptoms	Chest radiograph interpretation by radiologist	DSSM result†	GeneXpert result†
1	LAA	6/M	Yes	Cough >2 weeks, wheezing, weight loss; no improvement after taking antimicrobial drugs	Pneumonia, both paracardiac areas	Neg	Neg
2	LAA	2/M	Yes	Cough >2 weeks, weight loss, malaise; no improvement after taking antimicrobial drugs	Inflammatory process, both inner zones	Neg	Invalid, after 2 extractions
3	LAA	8/M	Yes	Cervical lymphadenopathy	Calcified hilar lymphadenopathy, likely representing a chronic process, such as pulmonary TB	Neg	Neg
4	LAA	14/M	Yes	None; history of prior TB treatment but did not complete therapy	Inflammatory process in left apical area compatible with chronic process, such as pulmonary TB with minimal apical pleural thickening	Neg	Neg
5	LAA	7/F	Yes	Cough >2 weeks	Normal	Neg	Neg
6	LAA	4/M	Yes	Cough >2 weeks, weight loss, anorexia, malaise, chest pain	Normal	Neg	Neg
7	LAA	5/M	Yes	Cervical lymphadenopathy	Inflammatory process in the left retrocardiac area	Neg	Neg
8	HAA	14/F	Yes	None	Normal	Neg	Pos
9	LAA	5/F	Yes	Cough >2 weeks, fever, weight loss	Normal	Neg	Pos
10	LAA	1/F	Yes	Cough >2 weeks, fever, dyspnea, no improvement after taking antimicrobial drugs	Normal	Neg	Neg
11	LAA	12/F	No	Coughing >2 weeks, fever, chest and back pain, weight loss, cervical lymphadenopathy	Normal	Neg	Neg
12	LAA	11/F	Yes	Cervical lymphadenopathy, no rales or wheezing	Normal	Neg	Neg
13	LAA	3/M	Yes	Cervical lymphadenopathy	Normal	Neg	Neg
14	LAA	6/M	Yes	Cervical lymphadenopathy	Normal	Neg	Neg
15	LAA	3/F	Yes	Coughing >2 weeks, weight loss	Bilateral pneumonia	Neg	Neg
16	HAA	10/M	Yes	Coughing >2 weeks, weight loss, cervical lymphadenopathy	Pneumonia, both lower lungs, minimal left pleural effusion vs. pleural thickening; consider Potts disease (extrapulmonary TB) involving T12 and L1 vertebrae with Gibbus deformity	Neg	Pos

*DSSM, direct sputum smear microscopy; HAA, heavily affected area; LAA, less affected area; neg, negative; pos, positive; TB, tuberculosis.
†Direct smears and GeneXpert (Cepheid, http://www.cepheid.com) performed on sputum for children >5 years of age and gastric aspirates for children <5 years of age.

Main Article

¹Additional members of the PEER Health Bohol Pediatric Study Team who contributed data are listed at the end of this article.

Page created: September 17, 2019

Page updated: September 17, 2019

Page reviewed: September 17, 2019

The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.

Volume 25, Number 10—October 2019

Research

Prevalence of Tuberculosis in Children After Natural Disasters, Bohol, Philippines

Table 5