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Volume 25, Number 11—November 2019

Research Letter

Middle East Respiratory Syndrome Coronavirus, Saudi Arabia, 2017–2018

Ahmed Hakawi, Erica Billig RoseComments to Author , Holly M. Biggs, Xiaoyan Lu, Mutaz Mohammed, Osman Abdalla, Glen R. Abedi, Ali A. Alsharef, Aref Ali Alamri, Samar Ahmad Bereagesh, Kamel M. Al Dosari, Saad Abdullah Ashehri, Waad Ghassan Fakhouri, Saleh Zaid Alzaid, Stephen Lindstrom, Susan I. Gerber, Abdullah Asiri, Hani Jokhdar, and John T. Watson
Author affiliations: Ministry of Health, Riyadh, Saudi Arabia (A. Hakawi, M. Mohammed, O. Abdalla, A.A. Alsharef, A.A. Alamri, S.A. Bereagesh, K.M. Al Dosari, S.A. Ashehri, W.G. Fakhouri, S.Z. Alzaid, A. Asiri, H. Jokhdar); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (E.B. Rose, H.M. Biggs, X. Lu, G.R. Abedi, S. Lindstrom, S.I. Gerber, J.T. Watson)

Main Article

Figure

Phylogenetic tree of MERS-CoV whole genome sequences obtained in Saudi Arabia (black dots) compared with 472 previously published human and camel genome sequences from GenBank. Tree inferred using MrBayes version 3.2.6 (https://nbisweden.github.io/MrBayes) under a general time-reversible model of nucleotide substitution with 4 categories of γ-distributed rate heterogeneity and a proportion of invariant sites. Box at the top of the tree on the left shows location of the tree on the right, showing

Figure. Phylogenetic tree of MERS-CoV whole-genome sequences obtained in Saudi Arabia (black dots) compared with 472 previously published human and camel genome sequences from GenBank. Tree inferred using MrBayes version 3.2.6 (https://nbisweden.github.io/MrBayes) under a general time-reversible model of nucleotide substitution with 4 categories of γ-distributed rate heterogeneity and a proportion of invariant sites. Box at the top of the tree on the left shows location of the tree on the right, showing lineage 5. Δ1 indicates 3-nt in-frame deletion in open reading frame 4a and Δ2 indicates 66-nt in-frame deletion in open reading frame 1a. Clade-credibility values >70% are indicated at selected nodes. Sequences from this study include GenBank accession numbers MK462243–MK462256 and MK483839. Scale bars indicate nucleotide substitutions per site. MERS-CoV, Middle East respiratory syndrome coronavirus; Hu, human; KSA, Kingdom of Saudi Arabia.

Main Article

Page created: October 16, 2019
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