Avian Influenza A Viruses among Occupationally Exposed Populations, China, 2014–2016
Chuansong Quan
1, Qianli Wang
1, Jie Zhang, Min Zhao, Qigang Dai, Ting Huang, Zewu Zhang, Shenghua Mao, Yifei Nie, Jun Liu, Yun Xie, Baorong Zhang, Yuhai Bi, Weifeng Shi, Peipei Liu, Dayan Wang, Luzhao Feng, Hongjie Yu
, William J. Liu
, and George F. Gao
Author affiliations: National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China (C. Quan, J. Zhang, P. Liu, D. Wang, W.J. Liu, G.F. Gao); Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China (C. Quan, W. Shi); Fudan University School of Public Health, Shanghai, China (Q. Wang, H. Yu); Institute of Microbiology, Chinese Academy of Sciences, Beijing (M. Zhao, Y. Bi, G.F. Gao); Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China (Q. Dai); Sichuan Provincial Center for Disease Control and Prevention, Chengdu, China (T. Huang); Dongguan Municipal Center for Disease Control and Prevention, Dongguan, China (Z. Zhang); Shanghai Municipal Center for Disease Control and Prevention, Shanghai (S. Mao); Henan Provincial Center for Disease Control and Prevention, Zhengzhou, China (Y. Nie); Zaozhuang Center for Disease Control and Prevention, Zaozhuang, China (J. Liu); Jiangxi Provincial Center for Disease Control and Prevention, Nanchang, China (Y. Xie); Aviation General Hospital, Beijing (B. Zhang); Chinese Center for Disease Control and Prevention, Beijing (L. Feng, G.F. Gao)
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Figure 4
Figure 4. Seroconversion and persistent positivity for avian influenza virus (AIV) A subtypes based on HI titers in a cohort study in China during December 2014–April 2016. Each dot and line connection represents 1 participant. Red dashed lines represent positive cutoff for the HI titers; HI–positive samples were confirmed by a microneutralization assay. A) Comparison of paired samples from participants during 2 surveillance periods showing seroconversion for 6 AIV subtypes. Weighted lines and dots represent participants with seroconversion. B) Number of participants with >2 positive sample who were persistently seropositive for 6 AIV subtypes. Weighted lines and dots represent number of participants with seropositivity. C) Antibody titers of representative participants with >1 positive sample in the 4 serosurveys. HI, hemagglutinin inhibition.
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