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Volume 25, Number 2—February 2019
Synopsis

Ebola Virus Infection Associated with Transmission from Survivors

Saskia Den Boon1Comments to Author , Barbara J. Marston1, Tolbert G. Nyenswah, Amara Jambai, Moumie Barry, Sakoba Keita, Kara Durski, Schabbethai S. Senesie, Devin Perkins, Anita Shah, Hugh H. Green, Esther L. Hamblion, Margaret Lamunu, Alex Gasasira, Nuha O. Mahmoud, Mamadou H. Djingarey, Oliver Morgan, Ian Crozier, and Christopher Dye
Author affiliations: World Health Organization, Geneva, Switzerland (S. Den Boon, K. Durski, D. Perkins, A. Shah, O. Morgan, I. Crozier, C. Dye); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (B.J. Marston, S.S. Senesie, H.H. Green, O. Morgan); National Public Health Institute, Monrovia, Liberia (T.G. Nyenswah); Ministry of Health and Sanitation, Freetown, Sierra Leone (A. Jambai); Ministry of Health, Conakry, Guinea (M. Barry, S. Keita); World Health Organization, Monrovia, Liberia (E.L. Hamblion, A. Gasasira, N.O. Mahmoud); World Health Organization, Freetown, Sierra Leone (M. Lamunu); World Health Organization, Conakry (M.H. Djingarey); University of Oxford, Oxford, UK (C. Dye)

Main Article

Table 2

Strength of evidence and criteria for source person for Ebola virus disease*

Strength of evidence Criteria
Strong, A + B + C A.Epidemiologic link between index person or first case and single proposed/probable source established
AND
B.EBOV RNA detected in a specimen taken from the proposed/probable source after recovery
AND
C.Sequencing indicates linkage to virus recovered from recipient or index person
Moderate, A + B or A + C A.Epidemiologic link between recipient or index person and proposed/probable source established
AND
B.EBOV RNA detected in a specimen taken from the proposed/probable source after recovery
OR
C.Sequencing indicates linkage to virus recovered from recipient or index person
Weak
 Epidemiologic link between recipient or index person and proposed/probable source established
Not identified No epidemiologic link between recipient or index person and proposed/probable source could be established

*Results of application of these criteria were included in the Appendix Table only when a single possible transmission scenario emerged after case investigation and review. EBOV, Ebola virus.

Main Article

1These authors contributed equally to this article.

Page created: January 18, 2019
Page updated: January 18, 2019
Page reviewed: January 18, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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