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Volume 25, Number 2—February 2019
Synopsis

Ebola Virus Infection Associated with Transmission from Survivors

Saskia Den Boon1Comments to Author , Barbara J. Marston1, Tolbert G. Nyenswah, Amara Jambai, Moumie Barry, Sakoba Keita, Kara Durski, Schabbethai S. Senesie, Devin Perkins, Anita Shah, Hugh H. Green, Esther L. Hamblion, Margaret Lamunu, Alex Gasasira, Nuha O. Mahmoud, Mamadou H. Djingarey, Oliver Morgan, Ian Crozier, and Christopher Dye
Author affiliations: World Health Organization, Geneva, Switzerland (S. Den Boon, K. Durski, D. Perkins, A. Shah, O. Morgan, I. Crozier, C. Dye); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (B.J. Marston, S.S. Senesie, H.H. Green, O. Morgan); National Public Health Institute, Monrovia, Liberia (T.G. Nyenswah); Ministry of Health and Sanitation, Freetown, Sierra Leone (A. Jambai); Ministry of Health, Conakry, Guinea (M. Barry, S. Keita); World Health Organization, Monrovia, Liberia (E.L. Hamblion, A. Gasasira, N.O. Mahmoud); World Health Organization, Freetown, Sierra Leone (M. Lamunu); World Health Organization, Conakry (M.H. Djingarey); University of Oxford, Oxford, UK (C. Dye)

Main Article

Table 3

Strength of evidence and criteria for sexual transmission of Ebola virus*

Strength of evidence Criteria
Strong, A + B + C A.Epidemiologic investigation identified sexual contact between recipient or index person and single proposed/probable source
AND
B.EBOV detected in single proposed/probable source’s semen or vaginal secretions (by a vaginal swab) by RT-PCR
AND
C.Sequencing indicates high likelihood of transmission to recipient
Moderate, A + B or A + C A.Epidemiologic investigation identified sexual contact between recipient or index person and single proposed/probable source
AND
B.EBOV detected in single proposed/probable source’s semen or vaginal secretions (by a vaginal swab) by RT-PCR
OR
C.Sequencing indicates high likelihood of transmission to recipient
Weak
 Epidemiologic investigation identified sexual contact between recipient or index person and single proposed/probable source†
None No report of sexual contact

*EBOV, Ebola virus; RT-PCR, reverse transcription PCR.
†If not countered by sequencing data suggesting that the sexual contact is unlikely to be the source.

Main Article

1These authors contributed equally to this article.

Page created: January 18, 2019
Page updated: January 18, 2019
Page reviewed: January 18, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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