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Volume 25, Number 2—February 2019
Research

Epidemiologic and Ecologic Investigations of Monkeypox, Likouala Department, Republic of the Congo, 2017

Reena H. DoshiComments to Author , Sarah Anne J. Guagliardo, Jeffrey B. Doty, Angelie Dzabatou Babeaux, Audrey Matheny, Jillybeth Burgado, Michael B. Townsend, Clint N. Morgan, Panayampalli Subbian Satheshkumar, Nestor Ndakala, Therese Kanjingankolo, Lambert Kitembo, Jean Malekani, Lem’s Kalemba, Elisabeth Pukuta, Tobi N’kaya, Fabien Kangoula, Cynthia Moses, Andrea M. McCollum, Mary G. Reynolds, Jean-Vivien Mombouli, Yoshinori Nakazawa, and Brett W. Petersen
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (R.H. Doshi, S.A.J. Guagliardo, J.B. Doty, A. Matheny, J. Burgado, M.B. Townsend, C.N. Morgan, P.S. Satheshkumar, A.M. McCollum, M.G. Reynolds, Y. Nakazawa, B.W. Petersen); Ministry of Health, Brazzaville, Democratic Republic of the Congo (A.D. Babeaux, L. Kitembo, F. Kangoula, J.-V. Mombouli); Oak Ridge Institute for Science and Education, Centers for Disease Control and Prevention Fellowship Program, Oak Ridge, Tennessee, USA (A. Matheny, J. Burgado, C.N. Morgan); Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo (N. Ndakala, T. Kanjingankolo, J.-V. Mombouli); University of Kinshasa, Kinshasa (J. Malekani, L. Kalemba); Institut Nationale de Recherche Biomedicale, Kinshasa (E. Pukuta); Ministere de l’Agriculture, de l’Elevage et de la Peche, Brazzaville (T. N’kaya); International Communication and Education Fund, Kinshasa (C. Moses)

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Table 2

Exposure histories, illness characteristics, laboratory results, and outcomes for confirmed, probable, and possible monkeypox cases, Likouala Department, Republic of the Congo, 2017

Case no.
Case category
Patient age, y/sex
Onset date
Orthopoxvirus*
District†
Outcome‡
Exposure
IgG
IgM
PCR
1e Confirmed 40/M Jan 18 No specimen No specimen Positive Enyelle Dead Unknown
2e Confirmed 9/M Jan 20 Unable to link Unable to link Positive Enyelle Alive Son of 1e
3e
Possible
24/M
Mar 21
Positive
Positive
No specimen
Enyelle
Alive
Unknown
1d Confirmed 12/F Jan 28 Positive Positive Positive Dongou Alive Hunter
2d Confirmed 4/F Feb 12 No specimen No specimen Positive Dongou Dead Contact with suspected case (never located)
3d Confirmed 28/F Feb 25 Positive Positive Positive Dongou Alive Hunter/bushmeat merchant, contact with 1d
4d Confirmed 20/F Mar 15 Positive Positive Positive Dongou Alive Hunter, contact with 1d, 3d, 15d
5d Probable 33/F Mar 24 Positive Positive Collected, lost Dongou Alive Mother of 2d
6d Probable 3/F Mar 30 Positive Positive No specimen Dongou Alive Family cluster, contact with 7d, 8d, 10–14d
7d Probable 1/F Unknown Positive Negative No specimen Dongou Alive Family cluster, contact with 6d, 8d, 10–14d
8d Probable 30/M Unknown Positive Positive Not collected Dongou Alive Hunter/family cluster, contact with 6d, 7d, 10–14d
9d Possible 27/F Unknown Positive Positive Not collected Dongou Alive Unknown
10d Probable 11/M Unknown Positive Positive No specimen Dongou Alive Hunter/family cluster, contact with 6–8d, 11–15d
11d Probable 15/F Unknown Positive Negative No specimen Dongou Alive Hunter/family cluster, contact with 6–8d, 10d, 12–14d
12d Probable 5/F Unknown Positive Positive No specimen Dongou Alive Family cluster, contact with 6–8d, 10d, 11d, 13d, 14d
13d Probable 5/F Unknown Positive Positive No specimen Dongou Alive Family cluster, contact with 6–8d, 10–12d, 14d
14d Probable 28/F Unknown Positive Positive Not collected Dongou Alive Hunter/family cluster, contact with 6–8d, 10–13d
15d
Probable
1/M
Unknown
Positive
Positive
Not collected
Dongou
Alive
Child of 3d
1i Probable 14/F Feb 2 No specimen No specimen No specimen Impfondo Dead Prepared bush meat for food (rats, rodents); sister of 2i–4i; first family member to fall ill
2i Confirmed 11/F Feb 24 Positive Positive Positive Impfondo Alive Sister of 1i, 3i, 4i
3i Probable 3/M Mar 4 Positive Positive No specimen Impfondo Alive Brother of 1i, 2i, 4i
4i Probable 8/M Mar 20 Positive Positive Collected, lost Impfondo Alive Brother of 1i, 2i, 3i

*Unable to link is defined as an inability to match specimens with the case report form because of coding errors; no specimen means that a specimen was never collected.
†All case-patients in Dongou were from Manfouété village.
‡Outcome is defined as patient status at the time of the investigation.

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Page created: January 18, 2019
Page updated: January 18, 2019
Page reviewed: January 18, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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