Table 1

Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men

Tim R.H. Read, Gerald L. Murray, Jennifer A. Danielewski, Christopher K. Fairley, Michelle Doyle, Karen Worthington, Jenny Su, Elisa Mokany, L.T. Tan, David Lee, Lenka A. Vodstrcil, Eric P.F. Chow, Suzanne M. Garland, Marcus Y. Chen, and Catriona S. Bradshaw

Author affiliations: Melbourne Sexual Health Centre, Carlton, Victoria, Australia (T.R.H. Read, C.K. Fairley, M. Doyle, K. Worthington, D. Lee, L.A. Vodstrcil, E.P.F. Chow, M.Y. Chen, C.S. Bradshaw); Monash University, Melbourne, Victoria, Australia (T.R.H. Read, C.K. Fairley, L.A. Vodstrcil, E.P.F. Chow, M.Y. Chen, C.S. Bradshaw); Monash Biomedicine Discovery Institute, Melbourne (G.L. Murray); Murdoch Children’s Research Institute, Parkville, Victoria, Australia (G.L. Murray, J.A. Danielewski, J. Su, S.M. Garland); Royal Women’s Hospital, Melbourne (G.L. Murray, J.A. Danielewski, S.M. Garland); Royal Children’s Hospital, Melbourne (G.L. Murray, S.M. Garland); SpeeDx Pty Ltd, Eveleigh, Sydney, New South Wales, Australia (E. Mokany, L.T. Tan); University of Melbourne, Melbourne (S.M. Garland)

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Characteristics associated with urethral or rectal Mycoplasma genitalium in asymptomatic men who have sex with men, Australia*

Characteristic	All patients	M. genitalium not detected	M. genitalium detected†	Crude OR (95% CI)	p value
Detected in urine, rectum, or both
Prevalence	1,001	906 (90.5)	95 (9.5, 7.7–11.5)
Median age, y (IQR)	28.8 (24.3–34.1)	28.9 (24.5–34.3)	27.4 (23.3–32.3)	0.96 (0.93–0.99)	0.006
HIV status‡
Negative	894	804 (88.7)	90 (94.7)
Positive	107	102 (11.3)	5 (5.3, 1.7–11.9)	0.44 (0.17–1.10)	0.08
On/commencing PrEP§
No	752	678 (84.3)	74 (82.2)
Yes	142	126 (15.7)	16 (17.8, 10.5–27.3)	1.16 (0.66–2.06)	0.60
Detected in urine only
Urine prevalence		974 (97.3)	27 (2.7, 1.8–3.9)
Insertive oral sex partners in previous 3 mo, n = 984¶
<4	431	421 (44.0)	10 (37.0)
>4	553	536 (56.0)	17 (63.0)	1.34 (0.61–2.95)	0.47
Insertive anal sex partners in previous 3 months, n = 941#
<2	428	418 (45.7)	10 (38.5)
>2	513	497 (54.3)	16 (61.5)	1.34 (0.60–3.0)	0.47
Condom use insertive anal sex in previous 3 mo
Always	287	280 (38.7)	7 (29.2)
Not always	460	443 (61.3)	17 (70.8)	1.53 (0.63–3.75)	0.35
Detected in rectum only
Rectal prevalence		931 (93.0)	70 (7.0, 5.5–8.8)
Receptive anal sex partners in previous 3 mo, n = 945#
<2	367	349 (39.8)	18 (26.1)
>2	578	527 (60.2)	51 (73.9)	1.88 (1.08–3.3)	0.026
Condom use receptive anal sex in previous 3 mo
Always	301	288 (37.1)	13 (20.0)
Not always	540	488 (62.9)	52 (80.0)	2.36 (1.24–4.81)	0.006

*Values are no. (%, 95% CI) except as indicated. This table should be viewed in conjunction with Table 2. IQR, interquartile range; OR, odds ratio; PrEP, preexposure prophylaxis.
†In 2 of 97 infected men, M. genitalium was detected in both the urine and the rectum.
‡Includes 5 men with unknown HIV infection status. M. genitalium was detected in 4.7% of HIV-positive men vs. 10.1% of HIV-negative men (p = 0.08).
§HIV-negative men only.
¶Median 4.
#Median 2.

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Page created: March 18, 2019

Page updated: March 18, 2019

Page reviewed: March 18, 2019

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