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Volume 25, Number 4—April 2019
Research

Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men

Tim R.H. Read, Gerald L. Murray, Jennifer A. Danielewski, Christopher K. Fairley, Michelle Doyle, Karen Worthington, Jenny Su, Elisa Mokany, L.T. Tan, David Lee, Lenka A. Vodstrcil, Eric P.F. Chow, Suzanne M. Garland, Marcus Y. Chen, and Catriona S. BradshawComments to Author 
Author affiliations: Melbourne Sexual Health Centre, Carlton, Victoria, Australia (T.R.H. Read, C.K. Fairley, M. Doyle, K. Worthington, D. Lee, L.A. Vodstrcil, E.P.F. Chow, M.Y. Chen, C.S. Bradshaw); Monash University, Melbourne, Victoria, Australia (T.R.H. Read, C.K. Fairley, L.A. Vodstrcil, E.P.F. Chow, M.Y. Chen, C.S. Bradshaw); Monash Biomedicine Discovery Institute, Melbourne (G.L. Murray); Murdoch Children’s Research Institute, Parkville, Victoria, Australia (G.L. Murray, J.A. Danielewski, J. Su, S.M. Garland); Royal Women’s Hospital, Melbourne (G.L. Murray, J.A. Danielewski, S.M. Garland); Royal Children’s Hospital, Melbourne (G.L. Murray, S.M. Garland); SpeeDx Pty Ltd, Eveleigh, Sydney, New South Wales, Australia (E. Mokany, L.T. Tan); University of Melbourne, Melbourne (S.M. Garland)

Main Article

Table 3

Detection of Mycoplasma genitalium, Chlamydia trachomatis, and Neisseria gonorrhoeae in asymptomatic men who have sex with men according to reports of symptoms during the preceding week, Australia*

Characteristic Urethral symptoms†
 Anorectal symptoms‡
None, no. (%)
 Mild, no. (%)
 Odds ratio (95% CI)
 p value
 None, no. (%)
 Mild, no. (%)
 Odds ratio (95% CI)
 p value
M. genitalium, n = 1,001
Not detected 889 (97.3) 85 (97.7) 692 (92.7) 239 (93.7)
Detected
 25 (2.7)
 2 (2.3)
 0.84 
(0.19–3.59)
 0.81
54 (7.2)
 16 (6.3)
 0.86 
(0.48–1.53)
 0.60
C. trachomatis, n = 958
Not detected 861 (98.4) 81 (97.6) 657 (91.4) 220 (92.1)
Detected
 14 (1.6)
 2 (2.4)
 1.52 
(0.34–6.80)
 0.59
62 (8.6)
 19 (7.9)
 0.92 
(0.54–1.56)
 0.75
Neisseria gonorrhoeae, n = 958
Not detected 868 (99.3) 83 (98.8) 675 (93.8) 228 (93.8)
Detected 6 (0.7) 1 (1.2) 1.74 
(0.21– 14.65) 0.61 45 (6.3) 15 (6.2) 0.99 
(0.54–1.80) 0.97

*All participants were triaged as asymptomatic. This table reports answers to a questionnaire about “any symptoms (even if mild) in the past week.”
†Urethral symptoms were any of the following: dysuria, discharge, urethral itch, or discomfort. No individual symptom was significantly associated with any organism.
‡Anorectal symptoms were any of the following: anal pain, bleeding, itch, or discomfort. No individual symptom was significantly associated with any organism.

Main Article

Page created: March 18, 2019
Page updated: March 18, 2019
Page reviewed: March 18, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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