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Volume 25, Number 7—July 2019
Research

Nationwide Stepwise Emergence and Evolution of Multidrug-Resistant Campylobacter jejuni Sequence Type 5136, United Kingdom

Bruno S. LopesComments to Author , Norval J.C. Strachan, Meenakshi Ramjee, Anne Thomson, Marion MacRae, Sophie Shaw, and Ken J. Forbes
Author affiliations: University of Aberdeen, Foresterhill, Aberdeen, Scotland, UK

Main Article

Table

Phenotypic evaluation of antimicrobial drug–resistant genotypes of Campylobacter jejuni ST5136 CC464 isolates, Scotland*

pubMLST ID Isolate Year Source gyrA C257T CIP OXA† AMP tet variant‡ TET aac3 variant KAN TOB
38459 ARI1530 2012 Human stool T R A S tet(O)80 R G1 R S
39121 ARI2250 2013 Human stool T R A S A S G1, G4 R S
41320 ARI3377 2014 Human stool T R OXA-465 R tet(O/32/O)7 R G1 R S
40661 ARI3044 2013 Human stool T R A S tet(O/M/O)218 R G1 R S
38785 ARI1899 2012 Human stool T R A S tet(O)13 R G1 R R
38883 ARI2002_1 2012 Human stool T R OXA-193 (G) S tet(O/32/O)7 R G1 R S
39844 C0525 2013 Turkey T R OXA-193 (T) R tet(O/32/O)7 R G1 R S
42202 C1204 2014 Chicken T R OXA-193 (T) R tet(O/32/O)7 R G1, G4 R R
40371 ARI2986 2013 Human stool T R OXA-193 (T) R tet(O/32/O)7 R G1, G4 I S
48290 ARI4158 2015 Human stool T R OXA-193 (T) R tet(O/32/O)7 R G1, G4 I S
42443 C1522 2015 Chicken T R OXA-193 (T) R tet(O/32/O)7 R G1, G4 R S
58497 C0112 2010 Chicken T R OXA-193 (T) R tet(O/32/O)7 R G1 R S
58473 ARI0533 2010 Human stool T R OXA-193 (T) R tet(O/32/O)7 R G1 R S
41611 C0972 2014 Chicken T R OXA-193 (T) R tet(O/32/O)7 R G2 I S
39810 C0469 2012 Turkey T R OXA-193 (T) R tet(O/32/O)7 R G1, G4 R S
58159 ARI3975 2015 Human stool C S OXA-193 (T) R tet(O/32/O)7 R G1, G4 R S
39411 ARI2623 2013 Human stool C S OXA-193 (T) R A S G1 R R
38522 ARI1599 2012 Human stool T R OXA-193 (T) R tet(O/32/O)7 R G1, G4 R R
38475 ARI1546 2012 Human stool T R A S tet(O/32/O)7 R G1 R R
48369 ARI3988 2015 Human stool T R A S tet(O/32/O)7 R G1 R S
42114 ARI3830 2015 Human stool C S OXA-193 (T) R tet(O/32/O)7 R G1, G4 R R
48290 ARI4158_20 2015 Human stool T R OXA-193 (T) R tet(O/32/O)7 R G1, G4 I S

*Result based on disk susceptibility testing, except for ampicillin, for which MIC was estimated. R indicates MIC >128mg/L. All isolates were sensitive to amikacin, gentamicin, and streptomycin. aac3, 3-N-aminoglycoside acetyltransferase gene groups (G1–G4); AMP, ampicillin; CC, clonal complex; CIP, ciprofloxacin; I, intermediate; ID, identification; KAN, kanamycin; R, resistant; S, sensitive; ST, sequence type as determined by multilocus sequence typing; TET, tetracycline; TOB, tobramycin.
†OXA-465 = blaOXA-184-like gene; A indicates absence of oxacillinase gene; (G) or (T) indicates guanine or thymine mutation at −10 promoter of blaOXA-193.
‡A indicates absence of tetracycline resistance gene.

Main Article

Page created: June 17, 2019
Page updated: June 17, 2019
Page reviewed: June 17, 2019
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