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Volume 26, Number 11—November 2020
Research

High Dengue Burden and Circulation of 4 Virus Serotypes among Children with Undifferentiated Fever, Kenya, 2014–2017

Melisa M. ShahComments to Author , Bryson A. Ndenga, Francis M. Mutuku, David M. Vu, Elysse N. Grossi-Soyster, Victoria Okuta, Charles O. Ronga, Philip K. Chebii, Priscilla Maina, Zainab Jembe, Carren M. Bosire, Jael S. Amugongo, Malaya K. Sahoo, ChunHong Huang, Jenna Weber, Sean V. Edgerton, Jimmy Hortion, Shannon N. Bennett, Benjamin A. Pinsky, and A. Desiree LaBeaud
Author affiliations: Stanford University School of Medicine, Stanford, California, USA (M.M. Shah, D.M. Vu, E.N. Grossi-Soyster, M.K. Sahoo, C. Huang, J. Weber, J. Hortion, B.A. Pinsky, A.D. LaBeaud); Kenya Medical Research Institute, Kisumu, Kenya (B.A. Ndenga, V. Okuta, C.O. Ronga); Technical University of Mombasa, Mombasa, Kenya (F.M. Mutuku, C.M. Bosire, J.S. Amugongo); Msambweni County Referral Hospital, Msambweni, Kenya (P.K. Chebii, P. Maina); Diani Health Center, Ukunda, Kenya (Z. Jembe); California Academy of Sciences, San Francisco, California, USA (S.V. Edgerton, S.N. Bennett); École Normale Supérieure de Lyon, Lyon, France (J. Hortion)

Main Article

Table 2

Clinical characteristics of febrile children stratified by dengue viremia status in study of dengue burden and circulation of 4 virus serotypes among children with undifferentiated fever, Kenya, 2014–2017*

Characteristic Participants with dengue viremia, n = 361 Participants without dengue viremia, n = 661 p value
Mean (SD) age, y 5.2 (3.4) 5.6 (3.9) 0.13
Mean (SD) temperature, °C 38.8 (0.6) 38.9 (0.7) 0.14
Mean (SD) no. illness days before seeking care
2.8 (1.6)
2.7 (1.5)
0.21
Sex
F 168 (46.5) 299 (45.2) 0.74
M
193 (53.5)
362 (54.8)
0.74
Signs and symptoms
Headache 179 (49.6) 326 (49.3) 0.99
Poor appetite 169 (46.8) 240 (36.3) 0.001
Cough 165 (45.7) 278 (42.1) 0.29
Joint pain 133 (36.8) 259 (39.2) 0.50
Nausea or vomiting 128 (35.5) 219 (33.1) 0.50
Chills 66 (18.3) 118 (17.9) 0.93
Abdominal pain 46 (12.7) 134 (20.3) 0.003
Diarrhea 42 (11.6) 68 (10.3) 0.58
Muscle aches
30 (8.3)
54 (8.2)
1.00
Malaria smear positive 150 (51.5) 291 (52.3) 0.88
DENV IgG present at febrile visit 14 (4.0) 12 (1.9) 0.07
Prescribed antimicrobial drugs 182 (50.4) 290 (43.9) 0.05
Prescribed antimalarial drugs 176 (48.8) 243 (36.8) <0.001

*Values are no. (%) unless indicated otherwise. DENV, dengue virus.

Main Article

Page created: August 06, 2020
Page updated: October 17, 2020 10:18 PM EDT
Page reviewed: October 17, 2020 10:18 PM EDT
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