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Volume 26, Number 11—November 2020
CME ACTIVITY - Research

Phage-Mediated Immune Evasion and Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus in Humans

Raphael N. Sieber, Tinna R. Urth, Andreas Petersen, Camilla H. Møller, Lance B. Price, Robert L. Skov, Anders R. Larsen, Marc Stegger1, and Jesper Larsen1Comments to Author 
Author affiliations: Statens Serum Institut, Copenhagen, Denmark (R.N. Sieber, T.R. Urth, A. Petersen, C.H. Møller, R.L. Skov, A.R. Larsen, M. Stegger, J. Larsen); Translational Genomics Research Institute, Flagstaff, Arizona, USA (L.B. Price, M. Stegger); George Washington University, Washington, DC, USA (L.B. Price)

Main Article

Figure 1

Maximum-likelihood phylogeny showing the genetic diversity of the 20 IEC-harboring ΦSa3int prophages identified in livestock-associated methicillin-resistant Staphylococcus aureus CC398 isolates from North Denmark Region, Denmark. Capital letters indicate phylogenetic clusters (A–E). Red text indicates ΦSa3int prophages harboring both immune evasion cluster and tarP (cluster E). The phylogeny was estimated for 795 high-quality core SNPs. Filled circles at nodes indicate bootstrap values >90%. Scale bar represents number of nucleotide substitutions per variable site.

Figure 1. Maximum-likelihood phylogeny showing the genetic diversity of the 20 IEC-harboring ΦSa3int prophages identified in livestock-associated methicillin-resistant Staphylococcus aureus CC398 isolates from North Denmark Region, Denmark. Capital letters indicate phylogenetic clusters (A–E). Red text indicates ΦSa3int prophages harboring both immune evasion cluster and tarP (cluster E). The phylogeny was estimated for 795 high-quality core SNPs. Filled circles at nodes indicate bootstrap values >90%. Scale bar represents number of nucleotide substitutions per variable site.

Main Article

1These senior authors contributed equally to this article.

Page created: September 11, 2020
Page updated: October 15, 2020
Page reviewed: October 15, 2020
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