Volume 26, Number 12—December 2020
Dispatch
Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020
William T. Hu
, J. Christina Howell, Tugba Ozturk, Karima Benameur, Leda C. Bassit, Richard Ramonell, Kevin S. Cashman, Shama Pirmohammed, John D. Roback, Vincent C. Marconi, Irene Yang, Valerie V. Mac, Daniel Smith, Ignacio Sanz, Whitney Wharton, F. Eun-Hyung Lee, and Raymond F. Schinazi
, J. Christina Howell, Tugba Ozturk, Karima Benameur, Leda C. Bassit, Richard Ramonell, Kevin S. Cashman, Shama Pirmohammed, John D. Roback, Vincent C. Marconi, Irene Yang, Valerie V. Mac, Daniel Smith, Ignacio Sanz, Whitney Wharton, F. Eun-Hyung Lee, and Raymond F. Schinazi
Table 2
Demographic and other information for a prospective cohort who recovered from an influenza-like illness, Atlanta, Georgia, USA, 2020
| Characteristic | IgG <0.82, IgM <2.00, n = 60 | IgG <0.82, IgM ≥2.00, n = 44 | IgG ≥0.82, IgM <2.00, n = 8 | IgG ≥0.82, IgM ≥2.00, n = 4 | p value |
|---|---|---|---|---|---|
| Symptom onset, no. (%) | 0.029 | ||||
| 7–29 d earlier | 23 (38) | 7 (16) | 1 (12) | 0 | |
| 30–60 d earlier |
37 (62) |
37 (84) |
7 (88) |
4 (100) |
|
| Sex, no. (%) | 0.042 | ||||
| F | 29 (48) | 33 (75) | 4 (50) | 3 (75) | |
| M |
31 (52) |
11 (25) |
4 (50) |
1 (25) |
|
| Median age, y (range) | 45.5 (19.4–73.7) | 34.9 (25.9–73.3) | 43.6 (31.7–62.3) | 37.3 (33.5–48.2) | 0.113 |
| Non-Hispanic Caucasian | 47 (78) | 36 (82) | 6 (75) | 4 (100) | 0.715 |
| Healthcare worker | 35 (58) | 27 (61) | 4 (50) | 2 (50) | 0.918 |
| Potential exposure to coronavirus disease | 37 (62) | 22 (50) | 5 (62) | 2 (50) | 0.662 |
| Never smoker |
51 (85) |
38 (86) |
7 (88) |
2 (50) |
0.119 |
| Clinical signs/symptoms | |||||
| Cough | 38 (63) | 37 (84) | 2 (25) | 4 (100) | 0.002 |
| Fever/chills | 21 (35) | 21 (48) | 2 (25) | 3 (75) | 0.214 |
| Shortness of breath | 21 (35) | 13 (29) | 1 (12) | 3 (75) | 0.166 |
| Myalgia | 34 (57) | 21 (48) | 4 (50) | 4 (100) | 0.228 |
| Headaches | 38 (63) | 21 (48) | 3 (37) | 3 (75) | 0.238 |
| Sore throat | 27 (45) | 25 (57) | 3 (37) | 4 (100) | 0.117 |
| Nasal congestion/rhinorrhea | 37 (62) | 30 (68) | 3 (37) | 0 | 0.029 |
| Diarrhea | 11 (18) | 13 (29) | 2 (25) | 2 (50) | 0.352 |
| Anosmia | 6 (10) | 5 (11) | 0 | 2 (50) | 0.067 |
| Fatigue | 1 (2) | 4 (9) | 0 | 0 | 0.262 |
| Vomiting | 2 (3) | 3 (7) | 0 | 0 | 0.717 |
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Page updated: November 19, 2020
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