Unique Clindamycin-Resistant Clostridioides difficile Strain Related to Fluoroquinolone-Resistant Epidemic BI/RT027 Strain
Andrew M. Skinner
, Laurica Petrella, Farida Siddiqui, Susan P. Sambol, Christopher A. Gulvik, Dale N. Gerding, Curtis J. Donskey, and Stuart Johnson
Author affiliations: Edward Hines, Jr. VA Hospital, Hines, Illinois, USA (A.M. Skinner, L. Petrella, F. Siddiqui, D.N. Gerding, S. Johnson); Loyola University Medical Center, Maywood, Illinois, USA (A.M. Skinner, S. Johnson); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.A. Gulvik); Louis Stokes VA Hospital, Cleveland, Ohio, USA (C.J. Donskey); Case Western Reserve University, Cleveland (C.J. Donskey)
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Figure 1
Figure 1. Comparison of the molecular characteristics of Clostridioides difficile strain DQ/591 and the epidemic BI/027 strain in study of C. difficile at 2 US Veteran Affairs long-term care facilities and their affiliated acute care facilities. The HindIII REA (A) and PCR ribotype (B) banding patterns were distinct between REA strain DQ/RT591 and REA strain BI/RT027. Molecular weight markers (in kb) are shown adjacent to the REA gel pattern. An internal spiked LIZ 1200 standard was used for fragment length calibrations (in bp) of the PCR ribotype gel patterns. REA, restriction endonuclease analysis.
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