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Volume 26, Number 2—February 2020
Research Letter

New Delhi Metallo-β-Lactamase-5–Producing Escherichia coli in Companion Animals, United States

Stephen D. Cole, Laura Peak, Gregory H. Tyson, Renate Reimschuessel, Olgica Ceric, and Shelley C. RankinComments to Author 
Author affiliations: University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA (S.D. Cole, S.C. Rankin); Louisiana State University, Baton Rouge, Louisiana, USA (L. Peak); US Food and Drug Administration, Silver Spring, Maryland, USA (G.H. Tyson, R. Reimschuessel, O. Ceric)

Main Article


Clinical characteristics of New Delhi metallo-β-lactamase-5–producing Escherichia coli isolates from 6 companion animals, United States, 2018*

Isolate ID BioSample accession no. Source Species Breed Age, y/sex Concurrent diagnosis Antimicrobial drugs in the past 30 days Outcome
24213-18 SAMN11230749 Endotracheal wash Canine Great Dane 11/F Megaesophagus; aspiration pneumonia AMP, CLI, CAZ, ENR, MTZ Discharged
24920-18 SAMN12190106 Lung tissue Canine Rottweiler 8/M Pheochormocytoma; aspiration pneumonia AMP, AZM, ENR, MTZ Discharged
27025-18-1, 27025-18-2 SAMN12189820, SAMN12190134 Urine (cystocentesis) Canine Mixed breed 13/F Atrioventricular block; acute kidney injury AMP, AZM, CFZ, ENR, MTZ Discharged
27241-18 SAMN12190501 Endotracheal wash Canine Beagle 5/M Septic peritonitis after foreign body removal; protein-losing nephropathy; suspected pulmonary thromobembolism AMP, AZM, FOX, PTZ, MTZ Euthanized
27609-18 SAMN12190410 Endotracheal wash Feline Domestic shorthair 8/F Asthma AZM Discharged
27614-18 SAMN12190436 Endotracheal wash Canine Standard poodle 8/F Laryngeal paralysis; pneumonia AZM, AMC, ENR Discharged

*All animals had been spayed or castrated. AMC, amoxicillin/clavulanate; AMP, ampicillin; AZM, azithromycin; CAZ, ceftazidime; CLI, clindamycin; CFZ, cefazolin; ENR, enrofloxacin; FOX, cefoxitin; ID, identification; MTZ, metronidazole; NCBI, National Center for Biotechnology Information; PTZ, piperacillin/tazobactam.

Main Article

Page created: January 20, 2020
Page updated: January 20, 2020
Page reviewed: January 20, 2020
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