Volume 26, Number 3—March 2020
Research
Acquisition of Plasmid with Carbapenem-Resistance Gene blaKPC2 in Hypervirulent Klebsiella pneumoniae, Singapore
Table 3
Antimicrobial drug group and drug | SGH10 | ENT494 | ENT646 | ENT1734 |
---|---|---|---|---|
Penicillins | ||||
Ampicillin | >64 | >64 | >64 | >64 |
Piperacillin |
32 |
>64 |
>64 |
>64 |
Cephems | ||||
Ceftriaxone |
<1 |
>64 |
>64 |
>64 |
Carbapenems | ||||
Imipenem | <1 | >64 | >64 | >64 |
Meropenem |
<1 |
8 |
16 |
8–16 |
Aminoglycosides | ||||
Amikacin | <1 | <1 | 2–4 | 4–8 |
Gentamicin | <1 | <1 | <1 | <1 |
Kanamycin |
2 |
4 |
16 |
32 |
Tetracyclines | ||||
Doxycycline |
<1 |
2 |
2 |
2 |
Fluoroquinolones | ||||
Ciprofloxacin | <1 | <1 | 8 | <1 |
Levofloxacin |
<1 |
<1 |
<1 |
<1 |
Folate pathway antagonists | ||||
Sulfamethoxazole | 128 | 512 | 512 | >512 |
Trimethoprim |
<1 |
<1 |
>64 |
<1 |
Phenicols | ||||
Chloramphenicol |
4 |
4–8 |
4–8 |
4 |
Fosfomycins | ||||
Fosfomycin |
>64 |
>64 |
>64 |
>64 |
Lipopeptides | ||||
Colistin | 4 | 2 | 2–4 | 2–4 |
Polymyxin B | 4 | 4 | 4 | 4 |
*Bold numbers indicate resistance as interpreted by Clinical and Laboratory Standards Institute interpretative criteria for MICs (38).
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