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Volume 26, Number 3—March 2020
Dispatch

Progressive Vaccinia Acquired through Zoonotic Transmission in a Patient with HIV/AIDS, Colombia

Katherine Laiton-Donato1Comments to Author , Paola Ávila-Robayo1, Andrés Páez-Martinez, Paula Benjumea-Nieto, José A. Usme-Ciro, Nicole Pinzón-Nariño, Ivan Giraldo, Diego Torres-Castellanos, Yoshinori Nakazawa, Nishi Patel, Kimberly Wilkins, Yu Li, Whitni Davidson, Jillybeth Burgado, Panayampalli Subbian Satheshkumar, Ashley Styczynski, Matthew R. Mauldin, Martha Gracia-Romero, and Brett W. Petersen
Author affiliations: Instituto Nacional de Salud, Bogotá, Colombia (K. Laiton-Donato, J.A. Usme-Ciro, M. Gracia-Romero); Hospital Universitario Mayor Méderi-Universidad del Rosario, Bogotá (P. Ávila-Robayo, P. Benjumea-Nieto, N. Pinzón-Nariño, I. Giraldo, D. Torres-Castellanos); Universidad de La Salle, Bogotá (A. Páez-Martínez); Universidad Cooperativa de Colombia, Santa Marta, Colombia (J.A. Usme-Ciro); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (Y. Nakazawa, N. Patel, K. Wilkins, Y. Li, W. Davidson, J. Burgado, P.S. Satheshkumar, A. Styczynski, M.R. Mauldin, B.W. Petersen)

Main Article

Table

Laboratory testing for orthopoxvirus diagnosis in an HIV/AIDS patient who acquired progressive vaccinia through zoonotic transmission, Colombia*

Sample date and type
 Serology
PCR
 Viral culture
IgM ELISA
 IgG ELISA
 Neutralization
titer
 OPXV-specific (Ct)
 Vaccinia-specific
2015 Mar
Serum Pos Pos 1:517
Scab Pos (31.9) Pos Pos
Scab
Pos (28.6)
 Pos
 Pos
2015 Jul
Serum Neg Pos 1:223
Scab, left leg Pos (36.2) Pos Pos†
Swab, left leg
Pos (29.2)
 Pos
 Pos†
2016 Apr
Paraffin block, left leg Neg
Paraffin block, left leg Neg
Paraffin block, left leg Neg

*Ct, cycle threshold; Neg, negative; Pos, positive.
†Slow-growing.

Main Article

1These authors contributed equally to this article.

Page created: February 20, 2020
Page updated: February 20, 2020
Page reviewed: February 20, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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