Volume 26, Number 8—August 2020
CME ACTIVITY - Synopsis
Tuberculosis in Internationally Displaced Children Resettling in Harris County, Texas, USA, 2010–20151
Table 4
Factors associated with a positive result for TST, IGRA, or both in 5,870 migrant children, Harris County, Texas, USA, 2010–2015*
Characteristic | TST model |
IGRA model |
TST and IGRA combined model |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
No.† | aOR (95% CI) | p value | No.† | aOR (95% CI) | p value | No.† | aOR (95% CI) | p value | |||
Age, y | |||||||||||
<2 | 53 | Referent | 10 | Referent | 55 | Referent | |||||
2–5 | 75 | 0.40 (0.26–0.61) | <0.001 | 13 | 0.26 (0.11–0.60) | 0.002 | 81 | 0.36 (0.24–0.54) | <0.001 | ||
6–10 | 43 | 0.72 (0.45–1.07) | 0.25 | 35 | 0.41 (0.20–0.85) | 0.02 | 74 | 0.28 (0.18–0.42) | <0.001 | ||
11–14 | 34 | 0.68 (0.39–1.21) | 0.19 | 56 | 1.05 (0.52–2.12) | 0.90 | 85 | 0.55 (0.37–0.83) | 0.004 | ||
>14 |
27 |
0.77 (0.44–1.35) |
0.36 |
47 |
1.35 (0.66–2.77) |
0.41 |
69 |
0.72 (0.48–1.10) |
0.13 |
||
Region of origin | |||||||||||
Southeast Asia | 99 | Referent | 62 | Referent | 149 | Referent | |||||
E. Mediterranean | 74 | 0.48 (0.33–0.70) | <0.001 | 30 | 0.34 (0.21–0.53) | <0.001 | 98 | 0.44 (0.33–0.59) | <0.001 | ||
Africa | 49 | 0.69 (0.45–1.07) | 0.10 | 61 | 1.02 (0.70–1.49) | 0.91 | 100 | 0.81 (0.61–1.09) | 0.17 | ||
Americas |
10 |
0.19 (0.09–0.39) |
<0.001 |
8 |
0.12 (0.06–0.25) |
<0.001 |
17 |
0.14 (0.08–0.23) |
<0.001 |
||
HIV positive | 5 | 2.99 (1.01–8.87) | 0.049 | 2 | – | – | 7 | 5.57 (2.23–13.90) | <0.001 |
*aOR, adjusted odds ratio; E., Eastern; IGRA, interferon gamma release assay; TST, tuberculin skin test; –, numbers too small to enable performance of these tests.
†Number in group with a positive TB test result.
1Preliminary results from this study were presented at the North American Union TB Conference, February 28–March 3, 2018, Chicago, IL, USA.
2Current affiliation: Harvard Medical School, Boston, Massachusetts, USA.