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Volume 26, Number 8—August 2020
CME ACTIVITY - Research

Sporadic Creutzfeldt-Jakob Disease among Physicians, Germany, 1993–2018

Peter Hermann1Comments to Author , Johannes Treig1, Steffen Unkel, Stefan Goebel, Timothy Bunck, Martha Jünemann, Tim Friede, and Inga Zerr
Author affiliations: University Medical Center Göttingen Department of Neurology, Göttingen, Germany (P. Hermann, J. Treig, S. Goebel, T. Bunck, M. Jünemann, I. Zerr); University Medical Center Göttingen Department of Medical Statistics, Göttingen (S. Unkel, T. Friede); German Center for Neurodegenerative Diseases, Göttingen (I. Zerr)

Main Article

Table 3

Physicians in cohorts of sCJD patients and in the whole population, Germany, 1993–2018*

Variable Physicians† Nonphysicians† OR (95% CI)‡ p value
Cohort A, 1993–2005)
sCJD patient
Known occupation 4 1,089 0.59 (0.16–1.52) 0.44
All 4 1,246 0.52 (0.14–1.33) 0.27
German population
 295,552
 47,611,282
Cohort B (2006–2016)
sCJD patient
Known occupation 13 426 4.09 (2.16–7.06) <0.001
All 13 1,478 1.18 (0.63–2.02) 0.54
German population
 382,545
 51,218,372
Validation cohort (2017-2018)
All sCJD patients 5 234§ 2.61 (1.08–6.33) 0.05
German population 424,413 51,924,527

*OR, odds ratio; sCJD, sporadic Creutzfeldt-Jakob disease.
†>35 years of age.
‡By Fisher exact test.
§Information about occupation was available for 88 patients.

Main Article

1These authors contributed equally to this article.

Page created: April 27, 2020
Page updated: July 15, 2020
Page reviewed: July 15, 2020
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