Differential Yellow Fever Susceptibility in New World Nonhuman Primates, Comparison with Humans, and Implications for Surveillance
Natália C.C. de Azevedo Fernandes
, Juliana M. Guerra, Josué Díaz-Delgado, Mariana S. Cunha, Leila delC. Saad, Silvia D. Iglezias, Rodrigo A. Ressio, Cinthya dos Santos Cirqueira, Cristina T. Kanamura, Isis P. Jesus, Adriana Y. Maeda, Fernanda G.S. Vasami, Júlia de Carvalho, Leonardo J.T. de Araújo, Renato Pereira de Souza, Juliana S. Nogueira, Roberta M.F. Spinola, and José L. Catão-Dias
Author affiliations: Instituto Adolfo Lutz, São Paulo, Brazil (N.C.C. de Azevedo Fernandes, J.M. Guerra, J. Díaz-Delgado, M.S. Cunha, S.D. Iglezias, R.A. Ressio, C. dos Santos Cirqueira, C.T. Kanamura, I.P. Jesus, A.Y. Maeda, F.G.S. Vasami, J. de Carvalho, L.T. de Araújo, R. Pereira de Souza, J.S. Nogueira); Universidade de São Paulo, São Paulo (N.C.C. de Azevedo Fernandes, J.M. Guerra, J. Díaz-Delgado, J.L. Catão-Dias); Texas A&M Veterinary Medical Diagnostic Laboratory, College Station, Texas, USA (J. Díaz-Delgado); Centro de Vigilância Epidemiológica Prof. Alexandre Vranjac, São Paulo (L.D.C. Saad, R.M.F. Spinola)
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Figure 3
Figure 3. Distribution of Cq values for yellow fever for concordant and discordant cases (A) and cases in different New World primates and in humans (B), Brazil. Box plots indicate Cq values among the groups, indicated by the y-axes, minimum, first quartile, third quartile, and maximum Cq values. Horizontal bars indicate medians. Circles indicate outlier Cq values, and red diamonds indicate mean Cq values. Concordance was determined by using immunohistochemical analysis (lesions and viral antigen in hepatocytes).
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