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Volume 27, Number 1—January 2021
Dispatch

Seventh Pandemic Vibrio cholerae O1 Sublineages, Central African Republic

Sebastien Breurec1, Thierry Franck12, Elisabeth Njamkepo, Jean-Robert Mbecko, Jean Rauzier, Hugues Sanke-Waïgana, Guyguy Kamwiziku, Renaud Piarroux, Marie-Laure Quilici3, and François-Xavier Weill3Comments to Author 
Author affiliations: Institut Pasteur de la Guadeloupe, Les Abymes, France (S. Breurec); INSERM Centre d’Investigation Clinique 1424, Pointe-à-Pitre/Les Abymes, France (S. Breurec); Université des Antilles, Pointe-à-Pitre, France (S. Breurec); Institut Pasteur de Bangui, Bangui, Central African Republic (S. Breurec, T. Franck, J.-R. Mbecko); Institut Pasteur, Paris, France (E. Njamkepo, J. Rauzier, M.-L. Quilici, F.-X. Weill); Université de Kinshasa, Kinshasa, Democratic Republic of the Congo (G. Kamwiziku); Assistance Publique-Hôpitaux de Paris, Paris (R. Piarroux)

Main Article

Table 2

Alterations of the wbeT (formerly rfbT) gene in Vibrio cholerae El Tor isolates from the Central African Republic*

Alteration no. Alteration type Genetic alteration Protein consequence† 7PET sublineage
A03 Premature stop codon G133T G45-to-STOP T7
B01 Premature stop codon Deletion TGTAC (nt 24–28) Frameshift after N7; then STOP T10
C19 Amino acid substitution G674A C225Y T9

*7PET, seventh pandemic Vibrio cholerae O1 El Tor.
†The codon number and single-letter amino acid abbreviation are shown (STOP corresponds to a stop codon).

Main Article

1These first authors contributed equally to this article.

2Deceased.

3These authors were joint principal investigators.

Page created: December 01, 2020
Page updated: December 21, 2020
Page reviewed: December 21, 2020
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