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Volume 27, Number 12—December 2021
Research

Surface‒Aerosol Stability and Pathogenicity of Diverse Middle East Respiratory Syndrome Coronavirus Strains, 2012‒2018

Neeltje van Doremalen1, Michael Letko1Comments to Author , Robert J. Fischer, Trenton Bushmaker, Jonathan Schulz, Claude K. Yinda, Stephanie N. Seifert, Nam Joong Kim, Maged G. Hemida, Ghazi Kayali, Wan Beom Park, Ranawaka A.P.M. Perera, Azaibi Tamin, Natalie J. Thornburg, Suxiang Tong, Krista Queen, Maria D. van Kerkhove, Young Ki Choi, Myoung-don Oh, Abdullah M. Assiri, Malik Peiris, Susan I. Gerber, and Vincent J. MunsterComments to Author 
Author affiliations: National Institutes of Health, Hamilton, Montana, USA (N. van Doremalen, M. Letko, R.J. Fischer, T. Bushmaker, J. Schulz, C.K. Yinda, S.N. Seifert, V.J. Munster); Washington State University, Pullman, Washington, USA (M. Leitko, S.N. Seifert); Seoul National University College of Medicine, Seoul, South Korea (N.J. Kim, W.B. Park, M.-d. Oh); King Faisal University, Al-Hasa, Saudi Arabia (M.G. Hemida); Kafrelsheikh University, Kafrelsheikh, Egypt (M.G. Hemida); University of Texas Health Sciences Center, Houston, Texas, USA (G. Kayali); University of Hong Kong, Hong Kong, China (R.A.P.M. Perera, M. Peiris); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Tamin, N.J. Thornburg, S. Tong, K. Queen, S.I. Gerber); World Health Organization, Geneva, Switzerland (M.D. van Kerkhove); Chungbuk National University, Cheongju City, South Korea (Y.K. Choi); Ministry of Health, Riyadh, Saudi Arabia (A.M. Assiri)

Main Article

Table

Characteristics of Middle East respiratory syndrome coronaviruses tested*

Name Host Year Location Full name GenBank accession no. SNPs >50%
EMC/12
 Human
 2012
 Saudi Arabia
 HCoV-EMC/2012
 JX869059
 G27162A (ORF5, W108†)
U/14
 Human
 2014
 United States
 Hu/Florida/USA-2/Saudi Arabia/2014
 KP223131
 None
KSA/15
 Human
 2015
 Saudi Arabia
Hu/Hofuf/KSA-11002/2015
 KY688120
 None
SK/15
 Human
 2015
 South Korea
 Hu/Korea/Seoul/177–3/2015
 KX034100
 C2149A (NSP2, S431Y); A6884G (synonymous); T9566C (synonymous); G10155T (NSP5, A46S); A11376T (NSP6, S147C); C14162T (synonymous); C26189T (ORF4b R33C)
KSA/18
 Human
 2018
 Saudi Arabia
Hu/Saudi Arabia/3015600912/2018
 MN723544
 C21149A (NSP16, L183I); G22366A† (S, R304Q); C25009T (S, S1185L)
C/KSA/13
 Camel
 2013
 Saudi Arabia
 Camel/Saudi Arabia/KFU-HKU1/2013
 KJ650297
 C25207T (S, S1251F); C27875T (M, T8I)
C/E/13
 Camel
 2013
 Egypt
 Camel/Egypt/NRCE/HKU270/2013
 KJ477103
 T16318C (synonymous); C24112T (S, A886V); 26892T (ORF5, P18L)
C/BF/15 Camel 2015 Burkina Faso Camel/Burkina Faso/CIRAD-HKU785/2015 MG923471 None

*NSP, nonstructural protein; ORF, open reading frame; SNP, single-nucleotide polymorphism. †Present in other sequences.

Main Article

1These authors contributed equally to this article.

Page created: August 26, 2021
Page updated: November 19, 2021
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