Volume 27, Number 12—December 2021
Research
Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in Households with Children, Southwest Germany, May–August 2020
Table 3
Association between coronavirus disease–related symptoms or hospitalization in index case-patients and secondary attack rates in exposed household members from 393 households with a symptomatic index case-patient whose hospitalization status is known, southwest Germany, May–August 2020*
Index case symptom or hospitalization | No. index cases, n = 393 | No. exposed, n = 1182 | No. seropositive exposed, n = 390 |
Observed SAR, % | Predicted SAR, % (IQR)† | Odds ratio (95% CI)† | p value† |
---|---|---|---|---|---|---|---|
Fever | 225 | 666 | 253 | 38.0 | 36.8 (11.8–58.4) | 1.93 (1.14–3.31) | 0.015 |
Cough | 236 | 717 | 272 | 37.9 | 36.8 (11.7–58.2) | 2.07 (1.21–3.53) | 0.008 |
Diarrhea | 91 | 271 | 94 | 34.7 | 33.2 (9.34–54.5) | 0.80 (0.43–1.49) | 0.481 |
Dysgeusia |
253 |
748 |
252 |
33.7 |
32.2 (10.4–48.7) |
1.41 (0.82–2.43) |
0.213 |
Hospitalization | 22 | 67 | 30 | 44.8 | 43.9 (15.2–68.9) | 1.22 (0.40–3.75) | 0.726 |
*IQR, interquartile range; NA, not applicable; SAR, secondary attack rate. †The predicted SARs, odds ratios, and p values were calculated from a multivariable generalized linear mixed-effects logistic regression model. The respective references were absence of the symptom or “hospitalization” and adjusted for age of index case-patient as a numeric variable (OR 1.04, 95% CI 1.01–1.06; p = 0.0055).
1These first authors contributed equally to this article.
2These senior authors contributed equally to this article.