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Volume 27, Number 12—December 2021
Dispatch

SARS-CoV-2–Specific Antibodies in Domestic Cats during First COVID-19 Wave, Europe

Claudia Schulz1, Byron Martina1, Monica Mirolo, Elisabeth Müller, Ruth Klein, Holger Volk, Herman Egberink, Mariana Gonzalez-Hernandez, Franziska Kaiser, Maren von Köckritz-Blickwede, and Albert OsterhausComments to Author 
Author affiliations: University of Veterinary Medicine Hannover, Hannover, Germany (C. Schulz, M. Mirolo, H. Volk, M. Gonzalez-Hernandez, F. Kaiser, M. von Köckritz-Blickwede, A. Osterhaus); Artemis One Health Research Foundation, Delft, the Netherlands (B. Martina, M. Mirolo); LABOklin, Kissingen, Germany (E. Müller, R. Klein); Utrecht University Faculty of Veterinary Medicine, Utrecht, the Netherlands (H. Egberink)

Main Article

Table 2

Comparison of diagnostic sensitivity and specificity of the RBD-ELISA and VNT in a study of SARS-CoV-2 seroprevalence among domestic cats during the first pandemic wave, Europe, April–August 2020*

Test results Value
RBD-ELISA sensitivity, % (95% CI) 90.6 (90.0–91.2)
RBD-ELISA specificity, % (95% CI) 99.8 (99.8–99.8)
No. positive (%; 95% CI), n = 2,160
RBD-ELISA and VNT 87 (4.0; 3.2–4.9)
RBD-ELISA only 92 (4.3; 3.5–5.2)
VNT only 96 (4.4; 3.6–5.4)

*A total of 5 samples were positive with RBD-ELISA and negative with VNT; 9 samples were positive with VNT but negative with RBD-ELISA. RBD-ELISA, receptor-binding domain–specific ELISA; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; VNT, virus neutralization test.

Main Article

1These authors contributed equally to this article.

Page created: September 01, 2021
Page updated: November 19, 2021
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