SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021
Jackie Kleynhans
, Stefano Tempia, Nicole Wolter, Anne von Gottberg, Jinal N. Bhiman, Amelia Buys, Jocelyn Moyes, Meredith L. McMorrow, Kathleen Kahn, F. Xavier Gómez-Olivé, Stephen Tollman, Neil A. Martinson, Floidy Wafawanaka, Limakatso Lebina, Jacques du Toit, Waasila Jassat, Mzimasi Neti, Marieke Brauer, Cheryl Cohen, and
for the PHIRST-C Group1
Author affiliations: National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa (J. Kleynhans, S. Tempia, N. Wolter, A. von Gottberg, J.N. Bhiman, A. Buys, J. Moyes, W. Jassat, M. Neti, C. Cohen); University of the Witwatersrand, Johannesburg (J. Kleynhans, S. Tempia, N. Wolter, A. von Gottberg, J.N. Bhiman, J. Moyes, C. Cohen); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Tempia, M.L. McMorrow); Influenza Program, Centers for Disease Control and Prevention, Pretoria, South Africa (M.L. McMorrow); MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand, Johannesburg (K. Kahn, F.X. Gómez-Olivé, S. Tollman, F. Wafawanaka, J. du Toit); Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg (N.A. Martinson, L. Lebina); Johns Hopkins University Center for TB Research, Baltimore, Maryland, USA (N.A. Martinson); Ampath Pathology, Pretoria (M. Brauer)
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Figure 4
Figure 4. Severe acute respiratory syndrome coronavirus 2 infection–case and infection–hospitalization ratios (A) and in-hospital and excess deaths infection-fatality ratios (B) in a rural and urban community during the first and second wave of infections, South Africa, March 2020–March 2021. Vertical lines represent 95% CIs. Wave 1: March 1–November 21, 2020. Wave 2: November 2020 22–March 27, 2021. ED, excess deaths; ICR, infection–case ratio; IFR, infection–fatality ratio; IH, in-hospital; IHR, infection–hospitalization ratio.
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