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Volume 27, Number 12—December 2021
Research

SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021

Jackie KleynhansComments to Author , Stefano Tempia, Nicole Wolter, Anne von Gottberg, Jinal N. Bhiman, Amelia Buys, Jocelyn Moyes, Meredith L. McMorrow, Kathleen Kahn, F. Xavier Gómez-Olivé, Stephen Tollman, Neil A. Martinson, Floidy Wafawanaka, Limakatso Lebina, Jacques du Toit, Waasila Jassat, Mzimasi Neti, Marieke Brauer, Cheryl Cohen, and for the PHIRST-C Group1
Author affiliations: National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa (J. Kleynhans, S. Tempia, N. Wolter, A. von Gottberg, J.N. Bhiman, A. Buys, J. Moyes, W. Jassat, M. Neti, C. Cohen); University of the Witwatersrand, Johannesburg (J. Kleynhans, S. Tempia, N. Wolter, A. von Gottberg, J.N. Bhiman, J. Moyes, C. Cohen); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Tempia, M.L. McMorrow); Influenza Program, Centers for Disease Control and Prevention, Pretoria, South Africa (M.L. McMorrow); MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), University of the Witwatersrand, Johannesburg (K. Kahn, F.X. Gómez-Olivé, S. Tollman, F. Wafawanaka, J. du Toit); Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg (N.A. Martinson, L. Lebina); Johns Hopkins University Center for TB Research, Baltimore, Maryland, USA (N.A. Martinson); Ampath Pathology, Pretoria (M. Brauer)

Main Article

Figure 5

Cutoff index (COI) on Roche Elecsys (Roche Diagnostics, https://www.roche.ch/en/standorte/rotkreuz.htm) anti–severe acute respiratory syndrome coronavirus 2 assay for persons with blood draws 1–5 samples who were seropositive at baseline (A) or showed seroconversion during blood draws 2–5, South Africa, July 2020–April 2021. Purple line indicates mean COI with 95% CIs. COI values in panel B are aligned to first draw before seroconversion, COI, cutoff index.

Figure 5. Cutoff index (COI) on Roche Elecsys (Roche Diagnostics, https://www.roche.ch/en/standorte/rotkreuz.htm) anti–severe acute respiratory syndrome coronavirus 2 assay for persons with blood draws 1–5 samples who were seropositive at baseline (A) or showed seroconversion during blood draws 2–5, South Africa, July 2020–April 2021. Purple line indicates mean COI with 95% CIs. COI values in panel B are aligned to first draw before seroconversion, COI, cutoff index.

Main Article

1Additional members of the PHIRST-C group who contributed to this manuscript are listed at the end of this article.

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Page updated: November 19, 2021
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