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Volume 27, Number 5—May 2021
Research

Clinical Evaluation of Roche SD Biosensor Rapid Antigen Test for SARS-CoV-2 in Municipal Health Service Testing Site, the Netherlands

Zsὁfia Iglὁi, Jans Velzing, Janko van Beek, David van de Vijver, Georgina Aron, Roel Ensing, Kimberley Benschop, Wanda Han, Timo Boelsums, Marion Koopmans, Corine Geurtsvankessel, and Richard Molenkamp

Author affiliations: Erasmus MC, Rotterdam, the Netherlands (Z. Igloi, J. Velzing, J. van Beek, D. van de Vijver, G. Aron, M. Koopmans, C. Geurtsvankessel, R. Molenkamp); Public Health Service Rotterdam-Rijnmond, Rotterdam (R. Ensing, T. Boelsums); National Public Health Institute (RIVM), Bilthoven, the Netherlands (K. Benschop, W. Han)

Main Article

Figure 2

Relationships of time from symptom onset to testing and cycle threshold values to results for rapid antigen detection tests and PCR for diagnosis of severe acute respiratory syndrome coronavirus 2, the Netherlands. A) Cycle thresholds of positive samples in relation to days since symptom onset, Ag RDT positivity, and culture outcomes of participation with known disease onset date (n = 140). B) PCR-positive samples by cycle threshold (n = 186) in relation to Ag RDT and culture test results. Ag RDT, antigen rapid detection test; Ct, cycle threshold; E gene, envelope gene; NA, not available; RT-PCR, reverse transcription PCR.

Figure 2. Relationships of time from symptom onset to testing and cycle threshold values to results for rapid antigen detection tests and PCR for diagnosis of severe acute respiratory syndrome coronavirus 2, the Netherlands. A) Cycle thresholds of positive samples in relation to days since symptom onset, Ag RDT positivity, and culture outcomes of participation with known disease onset date (n = 140). B) PCR-positive samples by cycle threshold (n = 186) in relation to Ag RDT and culture test results. Ag RDT, antigen rapid detection test; Ct, cycle threshold; E gene, envelope gene; NA, not available; RT-PCR, reverse transcription PCR.

Main Article

Page created: March 16, 2021
Page updated: April 20, 2021
Page reviewed: April 20, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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