Volume 27, Number 6—June 2021
Research Letter
Incursion of Novel Highly Pathogenic Avian Influenza A(H5N8) Virus, the Netherlands, October 2020
Nancy Beerens
, Rene Heutink, Frank Harders, Marit Roose, Sylvia B.E. Pritz-Verschuren, Evelien A. Germeraad, and Marc Engelsma
, Rene Heutink, Frank Harders, Marit Roose, Sylvia B.E. Pritz-Verschuren, Evelien A. Germeraad, and Marc Engelsma
Table
Calculated tMRCA with 95% HPD and posterior value for highly pathogenic avian influenza A(H5N8) virus, the Netherlands, October 2020*
| Segment | Node† | tMRCA |
Height 95% HPD | Posterior value | |
|---|---|---|---|---|---|
| Year | Date | ||||
| PB2 | 1 | ND | ND | ND | ND |
| 2 | 2016.67 | Sep 2016 | 2016.43–2016.88 | 0.61 | |
| 3 | 2016.47 | Jun 2016 | 2016.20–2016.68 | 0.97 | |
| 4 |
2012.70 |
Sep 2012 |
2010.50–2014.43 |
0.96 |
|
| PB1 | 1 | ND | ND | ND | ND |
| 2 | 2017.00 | Jan 2017 | 2016.79–2017.14 | 0.95 | |
| 3 | 2016.56 | Jul 2016 | 2016.35–2016.76 | 0.94 | |
| 4 |
2011.21 |
Mar 2011 |
2007.91–2013.81 |
1.00 |
|
| PA | 1 | ND | ND | ND | ND |
| 2 | 2016.67 | Sep 2016 | 2016.442016.88 | 0.01 | |
| 3 | 2016.48 | Jun 2016 | 2016.30–2016.67 | 1.00 | |
| 4 |
2008.70 |
Sep 2008 |
2005.77–2011.20 |
1.00 |
|
| HA | 1 | 2018.58 | Jul 2018 | 2018.15–2018.91 | 1.00 |
| 2 | 2017.18 | Mar 2017 | 2016.88–2017.44 | 1.00 | |
| 3 | 2016.62 | Aug 2016 | 2016.46–2016.78 | 1.00 | |
| 4 |
2015.97 |
Dec 2015 |
2015.68–2016.23 |
0.97 |
|
| NP | 1 | ND | ND | ND | ND |
| 2 | 2016.89 | Nov 2016 | 2016.52–2017.13 | 0.87 | |
| 3 | 2016.43 | Jun 2016 | 2016.08–2016.69 | 1.00 | |
| 4 |
2014.71 |
Sep 2014 |
2013.32–2015.77 |
0.95 |
|
| NA | 1 | 2018.42 | Jun 2018 | 2017.87–2018.88 | 1.00 |
| 2 | 2016.98 | Dec 2016 | 2016.80–2017.12 | 0.99 | |
| 3 | 2016.71 | Sep 2016 | 2016.51–2016.86 | 1.00 | |
| 4 |
2016.15 |
Feb 2016 |
2015.77–2016.40 |
1.00 |
|
| M |
A |
2016.39 |
May 2016 |
2015.84–2016.63 |
0.19 |
| NS | 1 | ND | ND | ND | ND |
| 2 | 2016.92 | Dec 2016 | 2016.70–2017.03 | 0.01 | |
| 3 | 2016.48 | Jun 2016 | 2016.00–2016.79 | 0.96 | |
| 4 | 2015.77 | Oct 2015 | 2014.74–2016.40 | 1.00 | |
*HA, hemagglutinin; HPD, highest posterior density interval; M, matrix protein; NA, neuraminidase; ND, not determined; NP, nucleoprotein; NS, nonstructural protein; PA, polymerase acidic, PB1, polymerase basic 1; PB2, polymerase basic 2; tMRCA, median time of the most recent common ancestor. †Nodes of the time-scaled phylogenetic tree.
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