Skip directly to page options Skip directly to A-Z link
Volume 27, Number 6—June 2021
CME ACTIVITY - Research

HIV Infection as Risk Factor for Death among Hospitalized Persons with Candidemia, South Africa, 2012–2017

Nelesh P. GovenderComments to Author , Jim Todd, Jeremy Nel, Mervyn Mer, Alan Karstaedt, Cheryl Cohen, and for GERMS-SA1
Author affiliations: University of Cape Town, Cape Town, South Africa (N.P. Govender); University of the Witwatersrand, Johannesburg (N.P. Govender, J. Nel, M. Mer, A. Karstaedt, C. Cohen); National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa (N.P. Govender, C. Cohen); London School of Hygiene and Tropical Medicine, London, UK (J. Todd)

Main Article

Table 4

Interaction between HIV and intensive care unit admission on in-hospital death among 907 persons with candidemia, adjusted for potential confounders, South Africa, 2012–2017*

Variable Stratum-specific aOR for death (95% CI) Wald test p value†
Admitted to ICU
HIV-seronegative Referent
HIV-seropositive
 1.56 (1.00–2.43)
 0.05
Not admitted to ICU
HIV-seronegative Referent
HIV-seropositive 2.27 (1.47–3.52) <0.001

*aOR, adjusted odds ratio; ICU, intensive care unit. 
†Overall likelihood ratio test for interaction p value = 0.22. Case-fatality ratio for those admitted to an ICU: HIV-seropositive (94/152; 62%), HIV-seronegative (157/301; 52%) versus those not admitted to an ICU: HIV-seropositive (117/224; 52%), HIV-seronegative (76/230; 33%).

Main Article

1Members of GERMS-SA are listed at the end of this article.

Page created: April 13, 2021
Page updated: May 19, 2021
Page reviewed: May 19, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external