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Volume 27, Number 6—June 2021
CME ACTIVITY - Research

HIV Infection as Risk Factor for Death among Hospitalized Persons with Candidemia, South Africa, 2012–2017

Nelesh P. GovenderComments to Author , Jim Todd, Jeremy Nel, Mervyn Mer, Alan Karstaedt, Cheryl Cohen, and for GERMS-SA1
Author affiliations: University of Cape Town, Cape Town, South Africa (N.P. Govender); University of the Witwatersrand, Johannesburg (N.P. Govender, J. Nel, M. Mer, A. Karstaedt, C. Cohen); National Institute for Communicable Diseases, a Division of the National Health Laboratory Service, Johannesburg, South Africa (N.P. Govender, C. Cohen); London School of Hygiene and Tropical Medicine, London, UK (J. Todd)

Main Article

Table 4

Interaction between HIV and intensive care unit admission on in-hospital death among 907 persons with candidemia, adjusted for potential confounders, South Africa, 2012–2017*

Variable Stratum-specific aOR for death (95% CI) Wald test p value†
Admitted to ICU
HIV-seronegative Referent
HIV-seropositive
 1.56 (1.00–2.43)
 0.05
Not admitted to ICU
HIV-seronegative Referent
HIV-seropositive 2.27 (1.47–3.52) <0.001

*aOR, adjusted odds ratio; ICU, intensive care unit. 
†Overall likelihood ratio test for interaction p value = 0.22. Case-fatality ratio for those admitted to an ICU: HIV-seropositive (94/152; 62%), HIV-seronegative (157/301; 52%) versus those not admitted to an ICU: HIV-seropositive (117/224; 52%), HIV-seronegative (76/230; 33%).

Main Article

1Members of GERMS-SA are listed at the end of this article.

Page created: April 13, 2021
Page updated: May 19, 2021
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