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Volume 28, Number 1—January 2022

Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007–2020

Charlotte Kaeuffer, Mathieu Baldacini, Tiffany Ruge, Yvon Ruch, Yves-Jean Zhu, Manon De Cian, Guillaume Philouze, Philippe Bachellier, Julie Denis, Nicolas Lefebvre, Francis Schneider, Yves Hansmann, Valérie Letscher-Bru, Raoul Herbrecht, Marcela Sabou, and François DanionComments to Author 
Author affiliations: Hôpitaux Universitaires de Strasbourg, Strasbourg, France (C. Kaeuffer, M. Baldacini, T. Ruge, Y. Ruch, Y.-J. Zhu, M. De Cian, G. Philouze, P. Bachellier, J. Denis, N. Lefebvre, F. Schneider, Y. Hansmann, V. Letscher-Bru, R. Herbrecht, M. Sabou, F. Danion); Institut de Cancérologie Strasbourg Europe, Strasbourg (R. Herbrecht); INSERM UMR-S1109, Strasbourg (F. Danion)

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Table 1

Clinical characteristics of Kazachstania spp. infections and colonizations, Strasbourg, France, 2007–2020*

Patient Age, y/sex Underlying condition Exposure Type of infection Therapy Outcome
1 67/F Diabetes, endometrial cancer (remission) Pigeon Fungemia + UTI FLC + CAS Survived
2 63/F Esophagus squamous cell carcinoma Pigeon Mediastinitis after gastric ulceration CAS Survived
3 66/M CDP (endocrine carcinoma), recurrent angiocholitis NA Angiocholitis FLC, surgery† Survived
4 84/F Esophageal achalasia None Esophagitis PPI, surgery‡ Survived
5 68/F CVID, gastro–jejunal anastomotic stenosis NA Colonization None Survived
6 46/M Caustic esophageal stenosis,
NA Colonization None Survived
7 59/F Systemic scleroderma NA Colonization None Died (cardiogenic shock)
8 40/M Former smoker, Staphylococcus ventilator-associated pneumonia NA Colonization None Survived
9 51/F AutoHSCT for oculo-cerebral NHL NA Colonization FLC Survived
10 60/M Proven Mycobacterium fortuitum infection NA Colonization None Survived
11 59/M COPD, emphysema, denutrition NA Colonization None Survived
12 77/M Congestive heart failure, ischemic cardiomyopathy, smoker NA Colonization None Died; multiorgan failure after cardiac surgery
13 66/M Angioimmunoblastic T-cell lymphoma, neutropenia, pulmonary tuberculosis NA Colonization None Died 5 mo later; cerebral toxoplasmosis, T-cell lymphoma progression

*AutoHSCT, autologous hematopoietic stem cell transplantation; CDP, cephalic duodenopancreatectomy; CAS, caspofungin; COPD, chronic obstructive pulmonary disease; CVID, common variable immunodeficiency; FLC, fluconazole; NHL, non-Hodgkin lymphoma; NA, not applicable; PPI, proton pump inhibitor; UTI, urinary tract infection. †Degastrogastrectomy and hepatico–jejunal and gastrointestinal anastomosis. ‡Peroral endoscopic myotomy to treat achalasia.

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Page created: November 10, 2021
Page updated: December 17, 2021
Page reviewed: December 17, 2021
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