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Volume 28, Number 11—November 2022
Dispatch

Effect of COVID-19 Pandemic on Invasive Pneumococcal Disease in Children, Catalonia, Spain

Pilar CiruelaComments to Author , Núria Soldevila, Juan José García-Garcia, Sebastià González-Peris, Alvaro Díaz-Conradi, Alba Redin, Belén Viñado, Conchita Izquierdo, Carmen Muñoz-Almagro, Angela Domínguez, and Barcino Working Group
Author affiliations: CIBER de Epidemiologia y Salud Pública, Madrid, Spain (P. Ciruela, N. Soldevila, J.J. García-García, C. Muñoz-Almagro, A. Dominguez); Agència de Salut Publica de Catalunya, Barcelona, Spain (P. Ciruela, C. Izquierdo); Universitat de Barcelona, Barcelona (N. Soldevila, J.J. García-García, A. Dominguez); Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain (J.J. García-García, A. Redin, C. Muñoz-Almagro); Institut de recerca Sant Joan de Déu, Esplugues de Llobregat (J.J. García-García, C. Muñoz-Almagro); Hospital Vall d’ Hebron, Barcelona (S. González-Peris, B. Viñado); Hospital HM Nens, Barcelona (A. Díaz-Conradi); Universitat Internacional de Catalunya, Sant Cugat del Vallés, Spain (C. Muñoz-Almagro)

Main Article

Table 1

Healthcare activity and IPD incidence by age group, Catalonia, Spain, 2018–2019 and 2020*

Variable No. cases (incidence, cases/100,000 population)
 IRR (95% CI) p value
Mean 2018–19 2020
All ages
Emergency department visits 227,148 (43,661.3) 148,637 (28,437.6) 0.65 (0.64–0.66) <0.0001
Hospital admissions 11,313 (2,174.5) 8,423 (1,611.5) 0.74 (0.72–0.76) <0.0001
Samples for culture, HSJD 7,489 (1,439.5) 7,106 (1,359.5) 0.94 (0.91–0.98) 0.001
Samples for PCR, HSJD and HVH 641 (123.2) 497 (95.1) 0.77 (0.69–0.87) <0.0001
IPD cases 57 (11.0) 20 (3.8) 0.35 (0.21–0.57) <0.0001
PCV13 serotypes 25 (4.8) 10 (1.9) 0.40 (0.18–0.82) 0.01
Serotype 3 17 (3.3) 9 (1.7) 0.53 (0.22–1.17) 0.07
Non-PCV13 serotypes
 29 (5.6)
 10 (1.9)
 0.34 (0.17–0.70)
 0.003
0–4 y
Emergency department visits 108,757 (93,016.7) 68,684 (60,617.9) 0.65 (0.64–0.66) <0.0001
Hospital admissions 6,519 (5,575.5) 4,256 (3,756.2) 0.67 (0.65–0.70) <0.0001
Samples for culture, HSJD ND ND NA NA
Samples for PCR, HSJD and HVH 459 (392.6) 342 (301.8) 0.77 (0.67–0.88) 0.0002
IPD cases 44 (37.6) 15 (13.2) 0.35 (0.19–0.62) 0.0001
PCV13 serotypes 18 (15.4) 8 (7.1) 0.46 (0.19–1.04) 0.06
Serotype 3 12 (10.3) 8 (7.1) 0.69 (0.27–1.69) 0.42
Non-PCV13 serotypes
 25 (21.4)
 7 (6.2)
 0.29 (0.12–0.67)
 0.002
5–17 y
Emergency department visits 118,391 (29,353.5) 79,953 (19,530.7) 0.66 (0.65–0.67) <0.0001
Hospital admissions 4,794 (1,188.6) 4,167 (1,017.9) 0.86 (0.82–0.89) <0.0001
Samples for culture. (HSJD ND ND NA NA
Samples for PCR. HSJD and HVH 182 (45.1) 155 (37.9) 0.84 (0.68–1.04) 0.11
IPD cases 13 (3.2) 5 (1.2) 0.38 (0.13–1.06) 0.06
PCV13 serotypes 7 (1.7) 2 (0.5) 0.28 (0.06–1.36) 0.17
Serotype 3 5 (1.2) 1 (0.2) 0.20 (0.02–1.69) 0.21
Non-PCV13 serotypes 4 (1.0) 3 (0.7) 0.74 (0.16–3.30) 0.71

*HSJD, Hospital Sant Joan de Dèu; HVH, Hospital Vall Hebron; IPD, invasive pneumococcal disease; IRR, incidence rate ratio; NA, not applicable; ND, not done; PCV13, 13-valent pneumococcal conjugate vaccine.

Main Article

Page created: September 22, 2022
Page updated: October 24, 2022
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