Hedgehogs as Amplifying Hosts of Severe Fever with Thrombocytopenia Syndrome Virus, China
Chaoyue Zhao, Xing Zhang, Xiaoxi Si, Ling Ye, Kevin Lawrence, Yajun Lu, Chunhong Du, Haidong Xu, Qian Yang, Qianfeng Xia, Guoxiang Yu, Wei Xu, Fei Yuan, Junfeng Hao
, Jia-Fu Jiang, and Aihua Zheng
Author affiliations: State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing (C. Zhao, F. Yuan, A. Zheng); CAS Center for Excellence in Biotic Interactions, University of the Chinese Academy of Sciences, Beijing, China (C. Zhao, X. Zhang, A. Zheng); College of Life Sciences, Henan Normal University, Xinxiang, China (X. Si); Daishan Center for Disease Control and Prevention, Zhoushan, Zhejiang, China (L. Ye); Massey University School of Veterinary Science, Palmerston North, New Zealand (K. Lawrence); Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, China (Y. Lu, Q. Xia); Yunnan Institute of Endemic Diseases Control and Prevention, Yunnan, China (C. Du); Shaozhuang Primary School, Weifang, China (H. Xu); Department of Infectious Disease, Yidu Central Hospital of Weifang, Weifang, Shandong, China (Q. Yang); Changdao National Nature Reserve Management Center, Yantai, Shandong, China (G. Yu); Xinyang Center for Disease Control and Prevention, Xinyang, Henan, China (W. Xu); Core Facility for Protein Research, Institute of Biophysics Chinese Academy of Sciences, Beijing (J. Hao); State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing (J. Jiang)
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Figure 6
Figure 6. Transmission of severe fever with thrombocytopenia syndrome virus (SFTSV) between Haemaphysalis longicornis ticks and Atelerix albiventris hedgehogs in study of hedgehogs as amplifying hosts of SFTSV in China. A, B) Weight change (A) and SFTSV viremia (B) in naive hedgehogs bitten by SFTSV-carrying adult ticks that were monitored for 12 d. Adult ticks were inoculated with SFTSV by feeding on SFTSV-infected hedgehogs. Numbers represent individual hedgehogs; the control animal was not bitten. C) SFTSV RNA level in engorged adult ticks from 3 hedgehogs. Each dot indicates 1 tick; horizontal lines indicate medians.
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