Hedgehogs as Amplifying Hosts of Severe Fever with Thrombocytopenia Syndrome Virus, China
Chaoyue Zhao, Xing Zhang, Xiaoxi Si, Ling Ye, Kevin Lawrence, Yajun Lu, Chunhong Du, Haidong Xu, Qian Yang, Qianfeng Xia, Guoxiang Yu, Wei Xu, Fei Yuan, Junfeng Hao
, Jia-Fu Jiang, and Aihua Zheng
Author affiliations: State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing (C. Zhao, F. Yuan, A. Zheng); CAS Center for Excellence in Biotic Interactions, University of the Chinese Academy of Sciences, Beijing, China (C. Zhao, X. Zhang, A. Zheng); College of Life Sciences, Henan Normal University, Xinxiang, China (X. Si); Daishan Center for Disease Control and Prevention, Zhoushan, Zhejiang, China (L. Ye); Massey University School of Veterinary Science, Palmerston North, New Zealand (K. Lawrence); Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, China (Y. Lu, Q. Xia); Yunnan Institute of Endemic Diseases Control and Prevention, Yunnan, China (C. Du); Shaozhuang Primary School, Weifang, China (H. Xu); Department of Infectious Disease, Yidu Central Hospital of Weifang, Weifang, Shandong, China (Q. Yang); Changdao National Nature Reserve Management Center, Yantai, Shandong, China (G. Yu); Xinyang Center for Disease Control and Prevention, Xinyang, Henan, China (W. Xu); Core Facility for Protein Research, Institute of Biophysics Chinese Academy of Sciences, Beijing (J. Hao); State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing (J. Jiang)
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Figure 4
Figure 4. Severe fever with thrombocytopenia syndrome virus (SFTSV) viremia in 4 Atelerix albiventris hedgehogs in study of hedgehogs as amplifying hosts of SFTSV in China. Hedgehogs were challenged by intraperitoneal inoculation with 4 × 106 FFU of SFTSV Wuhan strain and then kept at 4°C to trigger hibernation. Viremia in hedgehogs 1 and 2 was monitored at 15 days postinoculation and in hedgehogs 3 and 4 at 30 days postinoculation. Error bars indicate SDs.
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