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Volume 28, Number 12—December 2022
Research

Hedgehogs as Amplifying Hosts of Severe Fever with Thrombocytopenia Syndrome Virus, China

Chaoyue Zhao, Xing Zhang, Xiaoxi Si, Ling Ye, Kevin Lawrence, Yajun Lu, Chunhong Du, Haidong Xu, Qian Yang, Qianfeng Xia, Guoxiang Yu, Wei Xu, Fei Yuan, Junfeng HaoComments to Author , Jia-Fu Jiang, and Aihua ZhengComments to Author 
Author affiliations: State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing (C. Zhao, F. Yuan, A. Zheng); CAS Center for Excellence in Biotic Interactions, University of the Chinese Academy of Sciences, Beijing, China (C. Zhao, X. Zhang, A. Zheng); College of Life Sciences, Henan Normal University, Xinxiang, China (X. Si); Daishan Center for Disease Control and Prevention, Zhoushan, Zhejiang, China (L. Ye); Massey University School of Veterinary Science, Palmerston North, New Zealand (K. Lawrence); Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, Hainan Medical University, Haikou, China (Y. Lu, Q. Xia); Yunnan Institute of Endemic Diseases Control and Prevention, Yunnan, China (C. Du); Shaozhuang Primary School, Weifang, China (H. Xu); Department of Infectious Disease, Yidu Central Hospital of Weifang, Weifang, Shandong, China (Q. Yang); Changdao National Nature Reserve Management Center, Yantai, Shandong, China (G. Yu); Xinyang Center for Disease Control and Prevention, Xinyang, Henan, China (W. Xu); Core Facility for Protein Research, Institute of Biophysics Chinese Academy of Sciences, Beijing (J. Hao); State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing (J. Jiang)

Main Article

Figure 5

Pathology of severe fever with thrombocytopenia syndrome virus (SFTSV)–infected Atelerix albiventris hedgehogs in study of hedgehogs as amplifying hosts of SFTSV in China. Six hedgehogs were intraperitoneally inoculated with 4 × 106 FFU of SFTSV Wuhan strain, and 2 were mock infected with phosphate buffered saline solution as controls. Two hedgehogs were euthanized at 3 days, 6 days, and 2 months to test viral load in the organs. SFTSV viral load in organs was measured by real-time PCR.

Figure 5. Pathology of severe fever with thrombocytopenia syndrome virus (SFTSV)–infected Atelerix albiventris hedgehogs in study of hedgehogs as amplifying hosts of SFTSV in China. Six hedgehogs were intraperitoneally inoculated with 4 × 106 FFU of SFTSV Wuhan strain, and 2 were mock infected with phosphate buffered saline solution as controls. Two hedgehogs were euthanized at 3 days, 6 days, and 2 months to test viral load in the organs. SFTSV viral load in organs was measured by real-time PCR.

Main Article

Page created: November 08, 2022
Page updated: March 13, 2023
Page reviewed: March 13, 2023
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