West Nile Virus Transmission by Solid Organ Transplantation and Considerations for Organ Donor Screening Practices, United States
Raymond A. Soto

, Emily McDonald, Pallavi Annambhotla, Jason O. Velez, Janeen Laven, Amanda J. Panella, Kimberly D. Machesky, Jennifer L. White, Judie Hyun, Emily Freuck, Janice Habel, David Oh, Marilyn Levi, Rick Hasz, Elling Eidbo, J. Erin Staples, Sridhar V. Basavaraju, and Carolyn V. Gould
Author affiliations: Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (R.A. Soto, E. McDonald, J.O. Velez, J. Laven, A.J. Panella, J.E. Staples, C.V. Gould); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (P.D. Annambhotla, S.V. Basavaraju); Ohio Department of Health, Columbus, Ohio, USA (K.D. Machesky); New York Department of Health, Albany, New York, USA (J.L. White); Maryland Department of Health, Baltimore, Maryland, USA (J. Hyun); University of Cincinnati, Cincinnati, Ohio, USA (E. Freuck, J. Habel, D. Oh); Health Resources and Services Administration, Rockville, Maryland, USA (M. Levi); Association of Organ Procurement Organizations, Vienna, Virginia, USA (R. Hasz, E. Eidbo)
Main Article
Table 1
West Nile virus test results for organ donor and recipients, United States*
Person |
Specimen |
DRT |
RNA |
IgM |
Neutralizing antibodies (titer)† |
IgG |
Organ donor
|
Plasma |
−2 |
Detected |
|
|
|
Serum
|
−2
|
Detected
|
ND
|
ND
|
|
Liver recipient
|
Serum |
0 |
ND |
ND |
ND |
|
Serum |
18 |
ND |
Detected |
Detected (1;2,560) |
|
CSF |
22 |
|
Detected |
|
|
Serum
|
35
|
ND
|
Detected
|
|
|
Kidney recipient |
Serum |
15 |
|
Detected |
|
ND |
CSF |
18 |
|
Detected |
|
Detected |
Serum |
18 |
Detected |
Detected |
|
|
Whole blood |
18 |
Detected |
|
|
|
Urine |
18 |
Detected |
|
|
|
Serum |
25 |
ND |
Detected |
|
|
Whole blood |
25 |
Detected |
|
|
|
Main Article
Page created: November 03, 2021
Page updated: January 22, 2022
Page reviewed: January 22, 2022
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