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Volume 28, Number 2—February 2022
Research

Comparison of Complications after Coronavirus Disease and Seasonal Influenza, South Korea

Hyejin Lee1, Ho Kyung Sung1, Dokyoung Lee1, Yeonmi Choi, Ji Yoon Lee, Jin Yong Lee2Comments to Author , and Myoung-don Oh2Comments to Author 
Author affiliations: Seoul National University Bundang Hospital, Seongnam-si, South Korea (H. Lee); National Medical Center, Seoul, South Korea (H.K. Sung, M. Oh); Health Insurance Review & Assessment Service Research Institute, Wonju-si, South Korea (D. Lee, Y. Choi, J.Y. Lee, J.Y. Lee); Seoul National University Hospital, Seoul (J.Y. Lee); Seoul National University College of Medicine, Seoul (J.Y. Lee, M. Oh)

Main Article

Table 1

Baseline characteristics of participants in study comparing complications of COVID-19 and influenza, South Korea*

Characteristic General population† COVID-19 Influenza p value‡
Total no. participants
52,870,968
21,615
2,380,696

Sex 0.14
    M 26,455,169 (50.0) 9,700 (44.9) 1,080,288 (45.4)
    F
26,415,799 (50.0)
11,915 (55.1)
1,300,408 (54.6)

Age, y <0.001
    0–19 8,822,808 (16.7) 1,467 (6.8) 1,180,279 (49.6)
    20–44 18,223,124 (34.5) 7,665 (35.5) 531,254 (22.3)
    45–64 17,344,828 (32.8) 7,841 (36.3) 462,183 (19.4)
    65–74 4,907,575 (9.3) 2,755 (12.8) 11,5673 (4.9)
    ≥75
3,572,633 (6.8)
1,887 (8.7)
9,1307 (3.8)

Type of insurance <0.001
  Health insurance 51,344,938 (97.1) 20,218 (93.5) 2,327,645 (97.8)
  Medical aid
1,526,030 (2.9)
1,397 (6.5)
53,051 (2.2)

Region <0.001
   Seoul metropolitan area 26,724,640 (50.5) 12,386 (57.3) 1,070,695 (45.0)
   Daegu and Gyeongsangbuk province 5,111,575 (9.7) 4,963 (23.0) 256,833 (10.8)
   Other areas
21,034,753 (39.8)
4,266 (19.7)
1,053,168 (44.2)

Charlson Comorbidity Index score <0.001
    0 NA 13,467 (62.3) 1,533,247 (64.4)
    1–2 NA 6,484 (30.0) 755,602 (31.7)
    >3
NA
1,664 (7.7)
91,847 (3.9)

Severity NA <0.001
  Ambulatory state NA 5,224 (24.2) 2,151,801 (90.4)
  Hospitalized mild disease NA 15,447 (71.5) 222,572 (9.4)
  Hospitalized severe disease NA 944 (4.4) 6,323 (0.3)

*Values are no. (%) patients except as indicated. COVID-19, coronavirus disease; NA, not applicable. †Data source: 2020 National health insurance statistics. ‡χ2 tests were performed to assess the difference in proportion between COVID-19 and influenza patients.

Main Article

1These first authors contributed equally to this article.

2These corresponding authors contributed equally to this article.

Page created: December 08, 2021
Page updated: January 22, 2022
Page reviewed: January 22, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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