Volume 28, Number 3—March 2022
CME ACTIVITY - Synopsis
Rising Incidence of Legionnaires’ Disease and Associated Epidemiologic Patterns, United States, 1992–2018
Albert E. Barskey
, Gordana Derado, and Chris Edens
, Gordana Derado, and Chris Edens
Table
Magnitude of increase in age-standardized incidence of Legionnaires’ disease, cases/100,000 population, from 1992–2002 (average) through 2018, United States
| Demographic | Age-standardized average incidence, 1992–2002 | Age-standardized incidence, 2018 | Absolute increase in age-standardized incidence | Age-standardized incidence risk ratio, 2018 to 1992–2002 baseline (95% CI) | Increase in age-standardized incidence, % |
|---|---|---|---|---|---|
| Age group, y, not standardized | |||||
| 0–4 | 0.03 | 0.01 | −0.03 | 0.16 (0.02–1.19) | −83.52 |
| 5–14 | 0.02 | 0.01 | −0.01 | 0.48 (0.15–1.54) | −51.61 |
| 15–24 | 0.07 | 0.19 | 0.12 | 2.80 (2.19–3.57) | 179.80 |
| 25–34 | 0.18 | 0.75 | 0.58 | 4.30 (3.79–4.88) | 330.31 |
| 35–44 | 0.38 | 1.97 | 1.59 | 5.15 (4.74–5.59) | 414.89 |
| 45–54 | 0.66 | 4.12 | 3.46 | 6.28 (5.91–6.69) | 528.44 |
| 55–64 | 1.02 | 6.52 | 5.50 | 6.39 (6.05–6.75) | 539.14 |
| 65–74 | 1.42 | 7.66 | 6.24 | 5.40 (5.11–5.70) | 439.63 |
| 75–84 | 1.57 | 8.52 | 6.96 | 5.44 (5.07–5.84) | 444.13 |
| >85 |
1.49 |
9.69 |
8.20 |
6.50 (5.82–7.27) |
550.35 |
| Sex | |||||
| M | 0.63 | 3.66 | 3.04 | 5.86 (5.67–6.05) | 485.55 |
| F |
0.35 |
1.86 |
1.50 |
5.29 (5.06–5.53) |
429.22 |
| Race* | |||||
| Native American or Alaska Native | 0.26 | 1.27 | 1.01 | 4.93 (3.51–6.93) | 392.94 |
| Asian or Pacific Islander | 0.14 | 0.56 | 0.42 | 4.03 (3.19–5.10) | 303.18 |
| Black or African American | 0.47 | 5.21 | 4.74 | 11.04 (10.39–11.73) | 1003.95 |
| White |
0.37 |
1.99 |
1.61 |
5.30 (5.12–5.49) |
430.15 |
| Region | |||||
| Division | |||||
| Northeast | 0.68 | 4.82 | 4.14 | 7.04 (6.70–7.40) | 604.10 |
| New England | 0.61 | 4.33 | 3.72 | 7.10 (6.40–7.87) | 610.04 |
| Middle Atlantic | 0.71 | 5.00 | 4.30 | 7.07 (6.69–7.48) | 606.98 |
| South | 0.33 | 1.97 | 1.64 | 5.97 (5.67–6.29) | 497.23 |
| South Atlantic | 0.44 | 2.29 | 1.85 | 5.24 (4.91–5.59) | 423.54 |
| East South Central | 0.32 | 2.05 | 1.73 | 6.40 (5.63–7.27) | 539.66 |
| West South Central | 0.15 | 1.36 | 1.21 | 9.15 (8.10–10.34) | 815.03 |
| Midwest | 0.67 | 4.10 | 3.43 | 6.13 (5.85–6.42) | 513.06 |
| East North Central | 0.77 | 5.01 | 4.24 | 6.48 (6.16–6.82) | 548.02 |
| West North Central | 0.42 | 2.04 | 1.62 | 4.81 (4.29–5.40) | 381.38 |
| West | 0.29 | 0.99 | 0.70 | 3.39 (3.11–3.68) | 238.50 |
| Mountain | 0.43 | 1.07 | 0.64 | 2.47 (2.15–2.83) | 146.55 |
| Pacific |
0.23 |
0.95 |
0.72 |
4.13 (3.71–4.59) |
312.91 |
| United States | 0.48 | 2.71 | 2.23 | 5.67 (5.52–5.83) | 467.30 |
*Ethnicity was not analyzed because data were missing for 30.4% of cases.
Page created: January 05, 2022
Page updated: February 17, 2022
Page reviewed: February 17, 2022
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