Volume 28, Number 6—June 2022
Research
Effect of Recombinant Vesicular Stomatitis Virus–Zaire Ebola Virus Vaccination on Ebola Virus Disease Illness and Death, Democratic Republic of the Congo
Neil Rupani
, Mbong Eta Ngole, J. Austin Lee, Adam R. Aluisio, Monique Gainey, Shiromi M. Perera, Lina Kashibura Ntamwinja, Ruffin Mbusa Matafali, Rigo Fraterne Muhayangabo, Fiston Nganga Makoyi, Razia Laghari, Adam C. Levine, and Alexis S. Kearney
, Mbong Eta Ngole, J. Austin Lee, Adam R. Aluisio, Monique Gainey, Shiromi M. Perera, Lina Kashibura Ntamwinja, Ruffin Mbusa Matafali, Rigo Fraterne Muhayangabo, Fiston Nganga Makoyi, Razia Laghari, Adam C. Levine, and Alexis S. Kearney
Table 2
Frequency of symptoms reported by vaccinated and unvaccinated Ebola virus disease‒confirmed patients, Democratic Republic of the Congo
| Symptom |
Not vaccinated, n = 248, no. (%) |
Vaccinated, n = 137, no. (%) |
p value* |
| Asthenia† | 214 (86.6) | 102 (74.5) | 0.004 |
| Anorexia | 204 (82.3) | 80 (58.4) | <0.001 |
| Fever | 193 (77.8) | 99 (72.3) | 0.273 |
| Headache† | 156 (63.2) | 90 (65.7) | 0.700 |
| Abdominal pain | 152 (61.3) | 56 (40.9) | <0.001 |
| Nausea | 140 (56.5) | 50 (36.5) | <0.001 |
| Conjunctivitis† | 138 (55.9) | 49 (35.8) | <0.001 |
| Diarrhea† | 137 (55.5) | 45 (32.8) | <0.001 |
| Arthralgia | 134 (54.0) | 74 (54.0) | 1.000 |
| Myalgia | 128 (51.6) | 54 (39.4) | 0.029 |
| Chest pain† | 89 (36.0) | 32 (23.4) | 0.014 |
| Cough† | 75 (30.4) | 36 (26.3) | 0.466 |
| Bleeding‡ | 67 (27.1) | 14 (10.3) | <0.001 |
| Dysphagia | 61 (24.6) | 17 (12.4) | 0.007 |
| Sore throat† | 52 (21.1) | 17 (12.4) | 0.048 |
| Dyspnea† | 47 (19.0) | 13 (9.5) | 0.020 |
| Coma‡ | 16 (6.5) | 2 (1.5) | 0.050 |
| Confusion‡ | 14 (5.7) | 2 (1.5) | 0.090 |
| Rash‡ | 14 (5.7) | 5 (3.7) | 0.540 |
| Hiccup‡ | 14 (5.7) | 3 (2.2) | 0.188 |
| Jaundice† | 12 (4.9) | 2 (1.5) | 0.156 |
| Photophobia† | 5 (2.0) | 1 (0.7) | 0.588 |
*Boldface indicates a significant difference (p<0.05). †One patient had missing data for this symptom. ‡Two patients had missing data for this symptom.
Page created: March 31, 2022
Page updated: May 22, 2022
Page reviewed: May 22, 2022
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