Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 28, Number 7—July 2022
Research

Outbreak of IncX8 Plasmid–Mediated KPC-3–Producing Enterobacterales Infection, China

Lan Chen1, Wenxiu Ai1, Ying Zhou1, Chunyang Wu, Yinjuan Guo, Xiaocui Wu, Bingjie Wang, Lulin Rao, Yanlei Xu, Jiao Zhang, Liang ChenComments to Author , and Fangyou YuComments to Author 
Author affiliations: Ningbo First Hospital, Ningbo, China (L. Chen); First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China (W. Ai, C. Wu, L. Rao, J. Zhang, F. Yu); Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China (Y. Zhou, Y. Guo, X. Wu, B. Wang, Y. Xu, F. Yu); Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA (L. Chen); Hackensack Meridian School of Medicine, Nutley (L. Chen)

Main Article

Figure 4

The iteron difference between pCG2111-KPC-3 and p15WZ-82_KPC. A) p15WZ-82_KPC IncX8 plasmids have eight 22-bp iteron copies located upstream from the replication gene, whereas pCG2111-KPC-3 only has 7 copies of iteron and the seventh iteron (in comparison to p15WZ-82_KPC) was deleted. B) The sequences of the 8 iterons are listed and a SeqLog (https://pypi.org/project/seqlog) presentation of the conserved motif is shown. KPC, K. pneumoniae carbapenemase.

Figure 4. The iteron difference between pCG2111-KPC-3 and p15WZ-82_KPC. A) p15WZ-82_KPC IncX8 plasmids have eight 22-bp iteron copies located upstream from the replication gene, whereas pCG2111-KPC-3 only has 7 copies of iteron and the seventh iteron (in comparison to p15WZ-82_KPC) was deleted. B) The sequences of the 8 iterons are listed and a SeqLog (https://pypi.org/project/seqlog) presentation of the conserved motif is shown. KPC, K. pneumoniae carbapenemase.

Main Article

1These first authors contributed equally to this article.

Page created: May 05, 2022
Page updated: June 18, 2022
Page reviewed: June 18, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external