Volume 28, Number 8—August 2022
Research
Characterization of Emerging Serotype 19A Pneumococcal Strains in Invasive Disease and Carriage, Belgium
Table 1
Characteristics and antimicrobial drug susceptibility for serotype 19A strains of pneumococci isolated during the period after the PCV13 to PCV10 switch, Belgium*
Characteristic | IPD, young children | IPD, older persons | Carriage, young children | Total |
---|---|---|---|---|
No. strains |
54 |
56 |
56 |
166 |
Year of isolation |
2017–2018 |
2018 |
2017–2018 |
2017–2018 |
Age | ||||
0–11 mo | 41 | 0 | 8 | 49 |
13–23 mo | 13 | 0 | 32 | 45 |
2–3 y | 0 | 0 | 15 | 15 |
3–4 y | 0 | 0 | 1 | 1 |
65–85 y |
0 |
56 |
0 |
56 |
Sex, M/F |
32/22 |
27/29 |
28/28 |
87 |
Source of isolation | ||||
Blood | 48 | 56 | 0 | 104 |
CSF | 5 | 0 | 0 | 5 |
Pleural fluid | 1 | 0 | 0 | 1 |
Nasopharyngeal swab specimen |
0 |
0 |
56 |
56 |
Penicillin resistant | 7 (13.0) | 5 (11.1) | 3 (5.4) | 15 (9.0) |
Levofloxacin resistant | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
Erythromycin resistant | 16 (29.6) | 10 (17.9) | 13 (23.2) | 39 (23.5) |
Tetracycline resistant |
15 (27.8) |
10 (17.9) |
12 (21.4) |
37 (22.3) |
Pilus 1 | 25 (46.3) | 27 (48.2) | 27 (48.2) | 79 (47.6) |
Pilus 1 and pilus 2 | 3 (5.6) | 2 (3.6) | 4 (7.1) | 9 (5.4) |
*Values are no. or no. (%). CSF, cerebrospinal fluid; IPD, invasive pneumococcal disease; PCV, pneumococcal conjugate vaccine.