Volume 28, Number 8—August 2022
Research
Characterization of Emerging Serotype 19A Pneumococcal Strains in Invasive Disease and Carriage, Belgium
Table 2
Characteristics of serotype 19A pneumococcal sequence types after the PCV13 to PCV10 switch, Belgium*
GPSC | ST | No. | IPD in person <2 years of age | IPD in person >65 years of age | Carriage in children <3 years of age | Pilus 1 | No pilus | Penicillin resistant | Most frequent PBP profile | Erythromycin resistant | Resistance gene | Tetracycline resistant | Resistance gene |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GPSC4 |
ST416 | 79 | 26 | 26 | 27 | 76 | 3 | 0 | 0-0-0 (74); new-0-0 (3); 1-0-0 (2) | 17 | erm(B) | 15 | tetM |
ST2081 | 9 | 0 | 1 | 8 | 0 | 9 | 0 | 1-0-187 | 0 | ND | 0 | ND | |
ST419 | 5 | 0 | 1 | 4 | 0 | 5 | 0 | 1-0-187 | 0 | ND | 0 | ND | |
ST199 | 4 | 0 | 4 | 0 | 0 | 4 | 0 | 1-0-187 | 0 | ND | 0 | ND | |
ST3017 | 3 | 1 | 2 | 0 | 0 | 3 | 0 | 1-0-187 | 0 | ND | 0 | ND | |
ST15414 |
2 |
1 |
1 |
0 |
2 |
0 |
0 |
0-0-0 |
0 |
ND |
0 |
ND |
|
GPSC146 |
ST994 |
30 |
15 |
9 |
6 |
0 |
30 |
0 |
2-4-0 (29); new-4-0 (1) |
0 |
ND |
0 |
ND |
GPSC1 |
ST320 |
5 |
2 |
1 |
2 |
0 |
5 |
5 |
13-11-16 |
5 |
erm(B), mefA |
5 |
tetM |
GPSC11 |
ST193 |
4 |
1 |
0 |
3 |
0 |
4 |
0 |
2-0-2 (2); 2-0-3 (1) |
4 |
erm(B) |
3 |
tetM |
GPSC10 |
ST276 |
4 |
0 |
4 |
0 |
0 |
4 |
4 |
17-39-18 |
4 |
erm(B) |
4 |
ND |
GPSC109 |
ST13096 |
4 |
2 |
2 |
0 |
0 |
4 |
0 |
1-4-3 |
0 |
ND |
0 |
ND |
GPSC99 |
ST1848 |
3 |
0 |
0 |
3 |
0 |
3 |
0 |
New-44-0 (2); 2-44-2 (1) |
3 |
erm(B) |
3 |
tetM |
GPSC10 | ST15077 | 2 | 2 | 0 | 0 | 0 | 2 | 2 | 17-89-18 | 2 | erm(B) | 2 | tetM |
*GPSC, global pneumococcal sequence cluster; IPD, invasive pneumococcal disease; ND, not detected; PBP, penicillin-binding protein; PCV, pneumococcal conjugate vaccine; ST, sequence type.