Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 28, Number 8—August 2022
Dispatch

Zoonotic Threat of G4 Genotype Eurasian Avian-Like Swine Influenza A(H1N1) Viruses, China, 2020

Min Gu1, Kaibiao Chen1, Zhichuang Ge, Jun Jiao, Tianyu Cai, Suhan Liu, Xiaoquan Wang, Xinan Jiao, Daxin Peng, and Xiufan LiuComments to Author 
Author affiliations: Yangzhou University, Yangzhou, China (M. Gu, K. Chen, Z. Ge, J. Jiao, T. Cai, S. Liu, X. Wang, X. Jiao, D. Peng, X. Liu); Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou (M. Gu, X. Wang, X. Jiao, D. Peng, X. Liu)

Main Article

Figure 2

Pathogenicity of 2 G4 Eurasian avian-like influenza A(H1N1) swine isolates from pigs in China in BALB/c mice. A) Body weight change of infected mice. B) Survival curve of infected mice. Two groups of five 6-week-old BALB/c mice were inoculated intranasally with A/swine/Jiangsu/HD11/2020(H1N1) (HD11) or A/swine/Anhui/HD21/2020(H1N1) (HD21) at a dose of 106 50% egg infectious dose/50 µL. Another 5 mice mock-infected with phosphate-buffered saline were served as control. Body weight change and survival rate were recorded daily until 14 days postinoculation, and mice that lost ≥25% of the initial body weight were humanely euthanized.

Figure 2. Pathogenicity of 2 G4 Eurasian avian-like influenza A(H1N1) swine isolates from pigs in China in BALB/c mice. A) Body weight change of infected mice. B) Survival curve of infected mice. Two groups of five 6-week-old BALB/c mice were inoculated intranasally with A/swine/Jiangsu/HD11/2020(H1N1) (HD11) or A/swine/Anhui/HD21/2020(H1N1) (HD21) at a dose of 106 50% egg infectious dose/50 µL. Another 5 mice mock-infected with phosphate-buffered saline were served as control. Body weight change and survival rate were recorded daily until 14 days postinoculation, and mice that lost ≥25% of the initial body weight were humanely euthanized.

Main Article

1These authors contributed equally to this article.

Page created: June 23, 2022
Page updated: July 20, 2022
Page reviewed: July 20, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external