Volume 28, Number 9—September 2022
Dispatch
Creutzfeldt-Jakob Disease Incidence, South Korea, 2001–2019
Yong-Chan Kim and Byung-Hoon Jeong
Table
Annual cases and incidence of Creutzfeldt-Jakob disease, Korea, 2001–2019
| Year | Patients, no. (%) | Sex, no. (%) |
p value | Subtypes, no. (%) |
Total population | Incidence‡ | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| M | F | Sporadic | Iatrogenic† | Variant | Familial | |||||
| 2001 | 5 (0.86) | 2 (40) | 3 (60) | 0.7498 | 5 (100) | 0 | 0 | 0 | 47,370,164 | 0.11 |
| 2002 | 9 (1.55) | 5 (55.56) | 4 (44.44) | 0.6162 | 9 (100) | 0 | 0 | 0 | 47,644,736 | 0.19 |
| 2003 | 19 (3.28) | 7 (36.84) | 12 (63.16) | 0.3756 | 19 (100) | 0 | 0 | 0 | 47,892,330 | 0.40 |
| 2004 | 13 (2.25) | 8 (61.54) | 5 (38.46) | 0.3042 | 12 (92.31) | 0 | 0 | 1 (7.69) | 48,082,519 | 0.27 |
| 2005 | 15 (2.59) | 7 (46.67) | 8 (53.33) | 0.9705 | 14 (93.33) | 0 | 0 | 1 (6.67) | 48,184,561 | 0.31 |
| 2006 | 19 (3.28) | 11 (57.89) | 8 (42.11) | 0.3561 | 19 (100) | 0 | 0 | 0 | 48,438,292 | 0.39 |
| 2007 | 18 (3.11) | 13 (72.22) | 5 (27.78) | 0.0360 | 18 (100) | 0 | 0 | 0 | 48,683,638 | 0.37 |
| 2008 | 28 (4.84) | 15 (53.57) | 13 (46.43) | 0.5063 | 25 (89.29) | 0 | 0 | 3 (10.71) | 49,054,708 | 0.57 |
| 2009 | 30 (5.18) | 13 (43.33) | 17 (56.67) | 0.6829 | 29 (96.67) | 0 | 0 | 1 (3.33) | 49,307,835 | 0.61 |
| 2010 | 29 (5.01) | 14 (48.28) | 15 (51.72) | 0.9057 | 28 (96.55) | 1 (3.45) | 0 | 0 | 49,554,112 | 0.59 |
| 2011 | 29 (5.01) | 15 (51.72) | 14 (48.28) | 0.6302 | 26 (89.66) | 0 | 0 | 3 (10.34) | 49,936,638 | 0.58 |
| 2012 | 45 (7.77) | 23 (51.11) | 22 (48.89) | 0.6083 | 42 (93.33) | 0 | 0 | 3 (6.67) | 50,199,853 | 0.90 |
| 2013 | 34 (5.87) | 13 (38.24) | 21 (61.76) | 0.3112 | 31 (91.18) | 0 | 0 | 3 (8.82) | 50,428,893 | 0.67 |
| 2014 | 65 (11.23) | 31 (47.69) | 34 (52.31) | 0.9338 | 62 (95.38) | 0 | 0 | 3 (4.62) | 50,746,659 | 1.28 |
| 2015 | 33 (5.70) | 17 (51.52) | 16 (48.48) | 0.6252 | 33 (100) | 0 | 0 | 0 | 51,014,947 | 0.65 |
| 2016 | 43 (7.43) | 16 (37.21) | 27 (62.79) | 0.2073 | 173 (92.02)§ | 0 | 0 | 15 (7.98) | 51,217,803 | 0.84 |
| 2017 | 38 (6.56) | 13 (34.21) | 25 (65.79) | 0.1213 | – | – | – | – | 51,361,911 | 0.74 |
| 2018 | 54 (9.33) | 26 (48.15) | 28 (51.85) | 0.8883 | – | – | – | – | 51,606,633 | 1.05 |
| 2019 | 53 (9.15) | 24 (45.28) | 29 (54.72) | 0.7943 | – | – | – | – | 51,709,098 | 1.02 |
| Total | 579 (100) | 273 (47.15) | 306 (52.85) | – | 545 (94.13) | 1 (0.17) | 0 | 33 (5.70) | – | – |
*CJD includes possible, probable, and definite CJD diagnoses. Bold text indicates statistical significance (p<0.05). CJD, Creutzfeldt-Jakob disease; –, not applicable. †The source of transmission for the iatrogenic CJD case is dura mater graft. ‡Cases per million population §Reported cases and subtypes of CJD in South Korea, 2016–2019.
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