Volume 29, Number 10—October 2023
Research
Ancestral Origin and Dissemination Dynamics of Reemerging Toxigenic Vibrio cholerae, Haiti
Table
Bayesian hypothesis testing of monophyly used in a study of ancestral origin and dissemination dynamic of reemerging toxigenic Vibrio cholerae, Haiti*
Monophyly testing† | lml(ML)SS‡ | Ln(BF)SS§ | lml(ML)PS‡ | Ln(BF)PS§ |
---|---|---|---|---|
Monophyly enforced with Ogawa 2014–2018 clade | –1,985.9 | 95.3 | –1,988.4 | 94.5 |
*BF, Bayes factor; lml, log marginal likelihood; Ln, log; MCC, maximum clade credibility; ML, maximum-likelihood; SS, stepping-stone; PS, path sampling. †The test compares the MCC tree topology in Figure 5, panel B (H0), between 2022 environmental strains and 2018 environmental strain ENV515. Alternative topologies were obtained by enforcing monophyly with other strains (HA). ‡log of marginal likelihood estimates, lml(MLE), obtained by SS or PS by using a strict molecular clock and a Bayesian skyline demographic prior, with or without enforcing monophyly between the 2022 Haiti strains and different clinical strains. §log of BF comparing the null (H0) and alternative (HA) hypotheses.
1These senior authors contributed equally to this article.