Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 29, Number 11—November 2023
Research

Systematic Review and Meta-analysis of Deaths Attributable to Antimicrobial Resistance, Latin America

Agustín CiapponiComments to Author , Ariel Bardach, María Macarena Sandoval, María Carolina Palermo, Emiliano Navarro, Carlos Espinal, and Rodolfo Quirós
Author affiliations: Centro de Investigaciones Epidemiológicas y Salud Pública (CIESP), Buenos Aires, Argentina (A. Ciapponi, A. Bardach); Instituto de Efectividad Clínica y Sanitaria (IECS-CONICET), Buenos Aires (A. Ciapponi, A. Bardach, M.M. Sandoval, M.C. Palermo, E. Navarro); Florida International University, Miami, Florida, USA (C. Espinal, R. Quirós); Sanatorio Las Lomas, Buenos Aires (R. Quirós)

Main Article

Table

Pooled unadjusted odds ratio for the association between antimicrobial resistance and lethality by type of resistance, Latin America*

Type of resistance OR (95% CI) I2
Carbapenem-resistance 2.86 (2.07–3.95) 61%
Extended-spectrum β-lactamase 1.28 (0.95–1.74) 38%
Methicillin-resistance 1.78 (1.29–2.45) 63%
MDRO† 1.64 (1.16–2.30) 68%
Azol-resistant 1.41 (0.59–3.35) -
Vancomycin-resistant 4.09 (2.40–6.97) 0%
Random effect model 1.86 (1.55–2.23) 71%

*MDRO, multidrug-resistant organisms; OR, pooled odds ratio. †Multidrug-resistant organisms include methicillin-resistant Staphylococcus aureus, Vancomycin-resistant Enterococcus spp, extended-spectrum β-lactamase producing Enterobacterales, carbapenem-resistant Enterobacterales (including Klebsiella, Enterobacter, Escherichia coli, Proteus, Serratia), carbapenem-resistant Pseudomonas aeruginosa, carbapenem-resistant Acinetobacter baumannii and azole/echinocandin-resistant Candida spp.

Main Article

Page created: September 20, 2023
Page updated: October 23, 2023
Page reviewed: October 23, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external